Solubilization of Intraglomerular Deposits of Serum Proteins by Fresh Human Sera or Gamma-globulin in Patients with Diabetic Nephropathy
スポンサーリンク
概要
- 論文の詳細を見る
The solubilization of renal deposits of IgG and other serum proteins by fresh human sera or human gamma-globulin was studied in patients with diabetic nephropathy. Renal biopsy specimens were from 10 patients wth diabetic nephropathy. These specimens were incubated with fresh sera obtained from the same patients and healthy adults or human gamma-globulin at 37℃ for 1 hr in plastic test tubes. The sections were stained with FITC-labeled heavy chain specific anti-human IgG, al-anti-trypsin, haptoglobin and β-lipoprotein antisera, and then examined with a fluorescent microscope. It was demonstrated that fresh human sera or gamma-globulin significantly solubilized glomerular deposits of IgG and other serum proteins in patients with diabetic nephropathy. It was postulated that solubilization of protein deposits in glomeruli requires the same substances detected in vitro in the kidney tissues from patients with diabetic nephropathy.
- 東海大学の論文
著者
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Tomino Yasuhiko
Department Of Internal Medicine School Of Medicine Tokai University
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SUGA Takao
Department of Internal Medicine, School of Medicine, Tokai University
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NOMOTO Yasuo
Department of Internal Medicine, School of Medicine, Tokai University
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ENDOH Masayuki
Department of Internal Medicine, School of Medicine, Tokai University
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SAKAI Hideto
Department of Internal Medicine, School of Medicine, Tokai University
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Nomoto Yasuo
Departments Of Nephrology And Metabolism; School Of Medicine Tokai University
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Sakai Hideto
Division Of Nephrology And Metabolism Department Of Internal Medicine Tokai University School Of Med
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Endoh M
Division Of Nephrology And Metabolism Department Of Internal Medicine Tokai University School Of Med
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MIURA Masahiko
Department of Internal Medicine, School of Medicine, Tokai University
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YAGAME Mitsunori
Department of Internal Medicine, School of Medicine, Tokai University
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KANESHIGE Hideaki
Department of Internal Medicine, School of Medicine, Tokai University
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Shinbo Takao
The Division Of Nephrology And Metabolism Department Of Internal Medicine School Of Medicine Tokai U
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Inoue Wataru
Division Of Nephrology And Metabolism Department Of Internal Medicine School Of Medicine Tokai Unive
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Nomoto Yasuo
Division Of Nephrology And Metabolism Department Of Internal Medicine School Of Medicine Tokai Unive
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Nomoto Yasuo
Department Of Intermal Medicine School Of Medicine Tokai University
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Suga Takao
The Division Of Nephrology And Metabolism Department Of Internal Medicine School Of Medicine Tokai U
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Inoue Wataru
Department Of Intelligence Science And Technology Graduate School Of Informatics Kyoto University
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Sakai Hideto
Department Of Intermal Medicine School Of Medicine Tokai University
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TAMURA Shizue
Department of Internal Medcine, School of Medicine, Tokai University
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Tamura Shizue
Department Of Internal Medicine School Of Medicine Tokai University
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Nomoto Yasuo
Division Of Nephrology And Metabolism Department Of Internal Medicine Tokai University School Of Med
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Sakai Takako
The Division Of Nephrology And Metabolism Department Of Internal Medicine School Of Medicine Tokai U
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Miura Masahiko
Department Of Internal Medicine School Of Medicine Tokai University
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Yagame Mitsunori
The Division Of Nephrology And Metabolism Department Of Internal Medicine School Of Medicine Tokai U
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Suga Takao
Department Of Internal Medicine School Of Medicine Tokai University
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Kaneshige Hideaki
Division Of Nephrology And Metabolism Department Of Internal Medicine Tokai University School Of Med
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Kaneshige Hideaki
Division Of Nephrology And Metabolism Department Of Internal Medicine School Of Medicine Tokai Unive
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Sakai Hideto
Division Of Nephrology And Metabolism Department Of Internal Medicine School Of Medicine Tokai Unive
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Tomino Yasuhiko
Department Of Internal Medicine Fujita Health University
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Suga Takao
Division Of Nephrology Department Of Internal Medicine Tokai University Oiso Hospital
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Tomino Yasuhiko
Department Of Basic Medical Research And Education Ehime University Graduate School Of Medicine
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Kaneshige Hideaki
Division Of Nephrology And Metabolism Department Of Internal Medicine Tokai University School Of Med
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Endoh Masayuki
The Division Of Nephrology And Metabolism Department Of Internal Medicine School Of Medicine Tokai U
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Kaneshige Hideaki
Division Of Nephrology And Metabolism Department Of Internal Medicine Tokai University School Of Med
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Kaneshige Hideaki
Division Of Nephrology And Metabolism Department Of Internal Medicine School Of Medicine Tokai University
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Endoh Masayuki
The Division Of Nephrology And Metabolism Department Of Internal Medicine School Of Medicine Tokai University
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Sakai Hideto
Department Of Health Care Policy And Management Graduate School Of Comprehensive Sciences University Of Tsukuba
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Miura Masahiko
Department of Dental Radiology and Radiation Research, Faculty of Dentistry, Tokyo Medical and Dental University
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Inoue Wataru
Department of Electrical and Electronic Engineering, National Defense Academy, 1-10-20 Hashirimizu, Yokosuka, Kanagawa 239-8686, Japan
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