In Vitro Binding of Sulfobromophthalein to Cytoplasmic Protein from Liver, Kidney, and Small Intestinal Mucosa of Rat and Rabbit
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概要
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Sephadex G-75 gel filtration of cytoplasmic protein with BSP in vitro yielded elution patterns characteristic of the protein sources as liver, kidney, and small intestinal mucosa of rat and rabbit. In the both species, binding of sulfobromophthalein (BSP) with Y protein was observed to be predominant in the liver, and weak or not recognized in the kidney and small intestinal mucosa, as was to be expected. On the other hand, the BSP elution with Z protein fraction was appreciable in the rabbit kidney and the rat small intestinal mucosa, and it appeared that the role of Z protein on the fate of the organic anion in the body was not so simple. Two unknown fractions, Y'and Y"protein, were recognized in the BSP elution pattern with cytoplasmic protein of the rat kidney, and Y'protein was recognized in that of the rabbit kidney and small intestinal mucosa.
- 社団法人日本薬学会の論文
- 1976-07-25
著者
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森口 郁生
School of Pharmaceutical Sciences, Kitasato University
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梅山 秀明
School of Pharmaceutical Sciences, Kitasato University
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梅山 秀明
School Of Pharmaceutical Sciences Kitasato University
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森口 郁生
School Of Pharmaceutical Sciences Kitasato University
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松下 泰雄
School of Pharmaceutical Sciences, Kitasato University
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中川 節子
School of Pharmaceutical Sciences, Kitasato University
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松下 泰雄
School Of Pharmaceutical Sciences Kitasato University
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中川 節子
北里大学薬学部
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中川 節子
School Of Pharmaceutical Sciences Kitasato University
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