Protein Bindings. I. Binding of 2-(4'-Hydroxyphenylazo) benzoic Acid to Bovine Serum Albumin
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概要
- 論文の詳細を見る
Binding of anionic dye 2-(4'-hydroxyphenylazo) benzoic acid (HABA) to bovine serum albumin at pH 7.4 was studied spectrophotometrically. The relationship between albuminbound ratio of HABA and concentration of the unbound dye was expressed by a modified Langmuir-type equation involving a repulsing interaction. The binding becomes more difficult with the increasing bonds. The binding constant and the number of binding sites on albumin were evaluated in 0.05 M phosphate buffer solution and in 0.15 M tris. buffer solution at 25°and 37°.
- 公益社団法人日本薬学会の論文
- 1968-04-25
著者
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佐野 肇
Research Laboratories Chugai Pharmaceutical Co. Ltd.
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森口 郁生
School of Pharmaceutical Sciences, Kitasato University
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和田 栄
Research Laboratories, Chugai Pharmaceutical Co., Ltd.
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森口 郁生
Research Laboratories, Chugai Pharmaceutical Co., Ltd.
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和田 栄
Research Laboratories Chugai Pharmaceutical Co. Ltd.
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