高速液体クロマトグラフィーによる生薬分析 : オウレン, オウバク
スポンサーリンク
概要
- 論文の詳細を見る
For the analysis of Coptidis Rhizoma, high-speed liquid chromatography was examined, not only for its major alkaloid, berberine, but also for its minor alkaloids. It was found that under an appropriate condition [on starch gel (LS-170), eluted with the solvent system of H_2O : MeCN : AcOH : Et_3N=80 : 20 : 0.3 : 0.745,pH 8.5], sufficient separation of berberine, magnoflorine, jatrorrhizine, palmatine, coptisine, and some other unidentified alkaloids was obtained. By means of the present procedure, content of berberine and relative content of palmatine and coptisine to berberine in some of wild and commercial coptis rhizomes were determined. Since the solvent system does not contain any nonvolatile salt, the present technique also offers the possibility of application to rapidpreparative separation of alkaloids of this type by liquid chromatography. The application to analysis of alkaloids of phellodendron-cortex is also described.
- 公益社団法人日本薬学会の論文
- 1978-07-25
著者
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田中 治
広島大学医学部総合薬学科
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糸川 秀治
東京薬科大学 薬学部
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石川 治
大阪市工研
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橋本 勉
大阪府立成人病センター放射線診断科
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橋本 勉
東洋曹達工業(株)研究所
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田中 治
広島大学
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糸川 秀治
東京薬科大学
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