23 カボチャの花の成分研究
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概要
- 論文の詳細を見る
Eleven compounds isolated from growth-inhibiting active fraction of male flowers of Cucurbita pepo, were identified as p-hydroxybenzaldehyde (1), anisyl alcohol (2), p-hydroxybenzyl metyl ether (3), p-hydroxybenzyl alcohol (4), veratryl alcohol (5), isovanillyl alcohol (6), p-coumaric acid (7), phloretic acid (8), benzyl-β-D-glucoside (12), 4-methoxybenzyl-β-D-glucoside (13) and 3,4-dimethoxybenzyl-β-D-glucoside (14) and 4,5,6,12,13 and 14 are the first isolation from a natural source. Each compound was assayed about growth-inhibiting activity using lettuce seedlings. Four of them showed the strong activity, but same glycosides did not show the activity. Two new flavonol glycosides were also isolated from the inactive fraction and their structures determined by UV, NMR and Field desorption (FD)-MS as rhamnazin 3-rutinoside (24) and isorhamnetin 3-rutinoside-4'-rhamnoside (26). Isorhamnetin 3-rutinoside (25), eleven fatty acids, fourteen amino acids, two triterpenes, two sterols and these glucosides and two nucleic acids were also isolated. The electron impact (EI)-MS of flavonoid glycoside yield no information about the nature of the glycosidic units, while the FD-MS show the protonated molecular ion and is structurally more informative. However the FD-MS had several faults (technique, reappearance and etc.), so we tried to apply other soft ionizations such as In Beam (IB) EI, Chemical Ionization (CI) and Negative Ion Chemical Ionization (NICI). We now had good results about these spectra of eighteen flavonoid glycosides by the IB-NICI method.
- 天然有機化合物討論会の論文
- 1981-09-10
著者
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糸川 秀治
東京薬大
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糸川 秀治
東京薬科大学 薬学部
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生田 安喜良
東京薬科大学
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志田 保夫
東京薬科大学
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志田 保夫
東京薬科大学 薬学部
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押田 喜昭
東京薬大
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生田 安喜良
東京薬大
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志田 保夫
東京薬大
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稲富 秀夫
明治大・農
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押田 喜昭
東京薬科大学
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