含窒素異項環化合物のアンモ酸化に関する研究(第2報)Cr_2O_3-Al_2O_3触媒による3-ビコリンの気相アンモ酸化に関する速度論的研究

概要

論文の詳細を見る
The kinetics of heterogeneous vapor-phase ammoxidation of 3-picoline to 3-cyanopyridine was carried out over a Cr_2O_2-Al_2O_3 catalyst in a flow system. The reaction was carried out at atmospheric pressure and over the temperature range of 380° to 440°. The reaction rate was influenced by the partial pressure of 3-picoline and oxygen, but was not influenced by that of ammonia, 3-cyanopyridine or water. Experimental rate data were well interpreted by the Langmuir-Hinshelwood mechanism, where the rate-determining step was the surface reaction between adsorbed 3-picoline molecules and adsorbed oxygen atoms. The parameter values in the rate expression were estimated by nonlinear least squares analysis. The energy of activation for the ammoxidation of 3-picoline was ca. 36 kcal/mole, and the heats of adsorption for 3-picoline and oxygen were ca. 4.6 and 6.0 kcal/mole, respectively.
社団法人日本薬学会の論文
1972-12-25