A USEFUL MEASURE OF HEPATIC DRUG METABOLISM : TRIMETHADIONE ELIMINATION AS AN INDICATOR
スポンサーリンク
概要
著者
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TANAKA EINOSUKE
Department of Legal Medicine, Institute of Community Medicine
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KUROIWA YUKIO
Department of Biochemical Toxicology, School of Pharmaceutical Science Showa University
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Kuroiwa Y
Experimental Toxicology Group Sandoz Research Laboratory
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Kuroiwa Yukio
Department Of Biochemical Toxicology Faculty Of Pharmaceutical Sciences Showa University
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Kuroiwa Yukio
Department Of Biochemical Toxicology School Of Pharmaceutical Science Showa University
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KINOSHITA HARUKI
Department of Biochemical Toxicology, School of Pharmaceutical Sciences, Showa University
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TAKABATAKE EIGO
The Institute of Public Health
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Tanaka Einosuke
Institute Of Community Medicine And Institute Of Clinical Medicine University Of Tsukuba
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Tanaka Einosuke
Department Of Biochemical Toxicology School Of Pharmaceutical Sciences Showa University
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Kinoshita Haruki
Department Of Biochemical Toxicology School Of Pharmaceutical Science Showa University
関連論文
- TRIMETHADIONE TOLERANCE TEST FOR EVALUATION OF FUNCTIONAL RESERVE OF THE LIVER IN PATIENTS WITH LIVER CIRRHOSIS AND ESOPHAGEAL VARICES
- THE EFFECT OF INDOMETHACIN ON HEPATIC DRUG-OXIDIZING CAPACITY IN THE RAT : TRIMETHADIONE AND ANTIPYRINE METABOLISM AS AN INDICATOR
- A METHOD FOR ESTIMATION OF HEPATIC DRUG-METABOLIZING CAPACITY : DETERMINATION OF CONCENTRATION OF TRIMETHADIONE AND ITS METABOLITE IN HUMAN SERUM
- SELECTIVE EFFECT OF CHRONIC LEAD INGESTION III : EFFECT ON DOPAMINE β-HYDROXYLASE ACTIVITY IN BRAIN REGIONS OF RATS
- SELECTIVE EFFECT OF CHRONIC LEAD INGESTION ON TYROSINE HYDROXYLASE ACTIVITY IN BRAIN REGIONS OF RATS
- Simple and simultaneous determination for twelve phenothiazines in human serum by reversed-phase high-performance liquid chromatography
- Forensic analysis of eleven cyclic antidepressants in human biological samples using a new reversed-phase chromatographic column of 2μm porous microspherical silica gel
- Simultaneous determination of twelve benzodiazepines in human serum using a new reversed-phase chromatographic column on a 2-μm porous microspherical silica gel
- PHARMACOKINETIC STUDIES OF TRIMETHADIONE AND ITS METABOLITE IN RATS WITH CHEMICAL-INDUCED LIVER INJURY
- A USEFUL MEASURE OF HEPATIC DRUG METABOLISM : TRIMETHADIONE ELIMINATION AS AN INDICATOR
- Establishment and Peculiarity of Ouabain-resistant THP-1 cells
- COMPARISON OF THE EFFECT OF AN EQUIMOLAR AND LOW DOSE OF FENITROTHION AND METHYLPARATHION ON THEIR OWN METABOLISM IN RAT LIVER
- PROTECTIVE EFFECTS OF DIISOPROPYL 1, 3-DITHIOL-2-YLIDENE MALONATE (NKK-105) ON LIVER INJURY BY CARBON TETRACHLORIDE (CCl_4)
- ALTERATIONS OF HEPATIC MITOCHONDRIAL MONOAMINE OXIDASE ACTIVITY OF RATS DURING 2-ACETYLAMINOFLUORENE FEEDING
- Antigenic characterization in ampiroxicam-induced photosensitivity using an in vivo model of contact hypersensitivity
- Determination of plasma bromvalerylurea and its main metabolite by a simple high-performance liquid chromatographic method and quantitation of bromide by energy dispersive X-ray spectrometry in carbon tetrachloride-intoxicated rats
- Simultaneous determination of flunitrazepam and 7-aminoflunitrazepam in human serum by ion trap gas chromatography-tandem mass spectrometry
- Age-related changes in hepatic drug-oxidizing activity using trimethadione as a probe drug in human
- STUDIES ON THE MECHANISM OF INTERACTION BETWEEN METHAMPHETAMINE AND QUININE IN RATS
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- Selective Inhibition of Chondrogenic Differentiation in Embryonic Cells by a Teratogenic Compound
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- Comparative Studies on the Inducing Effects of Cobalt Chloride and Co-Protoporphyrin on Hepatic Ornithine Decarboxylase and Heme Oxygenase in Rats
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- RELATIONSHIP BETWEEN TRIMETHADIONE METABOLISM AND HEPATIC DRUG-OXIDIZING ENZYME ACTIVITIES IN DIFFERENT ANIMAL SPECIES
- STUDIES ON THE TRIMETHADIONE METABOLISM AS A TOOL FOR THE ASSESSMENT OF DRUG-METABOLIZING CAPACITY USING PLASMA AND URINE OF RATS PRETREATED WITH PHENOBARBITAL AND 3-METHYLCHOLANTHRENE
- DETERMINATION OF PLASMA TRIMETHADIONE AND ITS METABOLITE IN CARBON TETRACHLORIDE-INTOXICATED RATLIVER : A USEFUL TOOL FOR ESTIMATION OF HEPATIC DRUGMETABOLIZING CAPACITY
- SALIVA LEVELS OF TRIMETHADIONE AND ITS METABOLITE AS AN INDEX OF DRUG METABOLIZING ACTIVITY IN RATS
- Rharmacokinetics of Cephaeline and Emetine in Ipecac Syrup in Rats and Dogs
- A SUSTAINED INCREASE OF MICROSOMAL HEME OXYGENASE ACTIVITY FOLLOWING TREATMENT OF RATS WITH BACILLUS CALMETTE-GUERIN AND CORYNEBACTERIUM PARVUM : ITS POSSIBLE RELATION TO THE DECREASE OF CYTOCHROME P-450 CONTENT
- ALTERATIONS OF HEPATIC δ-AMINOLEVULINIC ACID SYNTHETASE, HEME OXYGENASE, MICROSOMAL CYTOCHROME CONTENT AND DRUG METABOLISM IN RATS BEARING ASCITIC TUMORS AH 13,AH 66 AND AH 414 AND A 3-METHYLCHOLANTHRENE INDUCED TUMOR
- INDUCTION OF HEME OXYGENASE AND INHIBITION OF δ-AMINOLEVULINIC ACID SYNTHETASE OF RAT LIVER BY THIOACETAMIDE AND THIOACETAMIDE-S-OXIDE
- The Metabolism and Excretion of Trimethadione in Patients with Percutaneous Transhepatic Biliary Drainage and Renal Dysfunction
- Sex-Related Differences in Hepatic Drug-Oxidizing Capacity of Streptozotocin-Induced Diabetic Rats
- TRIMETHADIONE METABOLISM IN PATIENTS WITH NORMAL LIVER AND IN PATIENTS WITH CHRONIC LIVER DISEASE
- HEPATIC TRIMETHADIONE-OXIDIZING CAPACITY REMAINS NORMAL IN PATIENTS WITH EXTRAHEPATIC CHOLELITHIASIS
- SELECTIVE EFFECT OF CHRONIC LEAD INGESTION II : EFFECT ON PHENYLETHANOLAMINE N-METHYLTRANSFERASE ACTIVITY IN BRAIN REGIONS OF RATS
- Simultaneous determination of carbamazepine and its metabolites in plasma from carbon tetrachloride-intoxicated rats using a new reversed-phase chromatographic column of 2-μm porous microspherical silica gel
- Simultaneous determination of plasma phenytoin and its primary hydroxylated metabolites in carbon tetrachloride-intoxicated rats by high-performance liquid chromatography
- Effect of propofol on ropivacaine metabolism in human liver microsomes
- Effects of clonidine on lidocaine metabolism in human or rat liver microsomes
- Propofol inhibits lidocaine metabolism in human and rat liver microsomes
- STUDIES ON THE LIVER ENLARGEMENT INDUCED BY DIETARY ADMINISTRATION OF DI-(2-ETHYLHEXYL) PHTHALATE (DEHP).
- COMPARATIVE STUDY OF LIVER ENLARGEMENT INDUCED BY VARIOUS CHEMICALS
- SIMULTANEOUS INDUCTION OF ORNITHINE DECARBOXYLASE AND HEME OXYGENASE UNDER VARIOUS EXPERIMENTAL CONDITIONS
- Clinical significance of the trimethadione tolerance test in chronic hepatitis: A useful indicator of hepatic drug metabolizing capacity
- COMBINED EFFECTS OF POLYCHLORINATED BIPHENYLS AND METHYLMERCURY ON HEPATIC MICROSOMAL MONOOXYGENASES AND THE HEPATOTOXIC ACTION OF BROMOBENZENE
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- AN INDUCTION OF HEME OXYGENASE AND ITS POSSIBLE RELATION TO THE DECREASE OF CYTOCHROME P-450 CONTENT DURING LIVER REGENERATION
- ALTERATIONS OF DRUG AND HEME METABOLIZING ENZYMES DURING LIVER REGENERATION
- EFFECT OF HEAVY METALS ON SOME ENZYMES OF RAT LIVER AND FACTORS WHICH MODIFY THE METAL ACTIONS, ESPECIALLY OF CADMIUM
- INHIBITION OF MONOAMINE OXIDASE BY 3-METHYL-4-DIMETHYLAMINO AZOBENZENE (3-Me-DAB) IN RAT LIVER MITOCHONDRIA
- EFFECTS OF PASSIVE IMMUNIZATION WITH RABBIT ANTI-PHENOBARBITAL IgG ON CYCLOBARBITAL-INDUCED SLEEPING TIME AND HEPATIC ENZYME ACTIVITIES OF C3H MICE
- GENERATION AND DISTRIBUTION OF METHYLMERCURY IN AQUATIC SYSTEMS
- TRIMETHADIONE AS A MODEL DRUG FOR THE EVALUATION OF HEPATIC DRUG-METABOLIZING CAPACITY IN NORMAL AND D-GALACTOSAMINE INTOXICATED RATS
- PRODUCTION OF TOLERANCE TO FENITROTHION I N MALE RATS
- The effect of H2-receptor antagonists on antipyrine and pentobarbital metabolism in male and female rats.
- Early effects of 2-acetylaminofluorene and N-hydroxy-2-acetylaminofluorene on mitochondrial outer membrane enzyme activities of rat liver.
- The Impact of Liver Cirrhosis and Cholelithiasis on Phase I and II Reactions Using Antipyrine and Trimethadione as a Model Substrate.
- The role of vagal reflex in mechanism of secretagogic action of bromhexine.
- Antipyrine metabolism in female Lewis and Dark Agouti strains of rats, which are extensive and poor metabolizers of debrisoquine, respectively.