EXCITATION BY LYONIOL-A OF VAGAL AFFERENT NERVES AND THE REFLEX AUTONOMIC AND SOMATIC ACTIONS IN RATS
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概要
- 論文の詳細を見る
Lyoniol-A (2 mg/kg, i.v.), a toxic component isolated from the Ericaceous tree, markedly caused the increase in rate of discharges from vagal afferent nerves in the rat. This agent also caused respiratory depression, hypotension and the relief of decerebrate rigidity. These effects of lyoniol-A on the respiration and the rigidity were absent under conditions of bilateral cervical vagotomy, and the hypotension was abolished by sectioning of both vagal and carotid sinus nerves. These results suggest that the excitation by lyoniol-A of the afferent activities reflexly produces respiratory depression, hypotension and the relief of decerebrate rigidity.
- 公益社団法人日本薬学会の論文
著者
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FUKUDA Hideomi
Department of Pharmacology, College of Pharmacy, Nihon University
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Fukuda H
Department Of Pharmacology College Of Pharmacy Nihon University
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Fukuda Hideomi
Department Of Pharmacology College Of Pharmacy Nihon University
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Kudo Yoshihisa
Laboratory Of Neuropharmacology Mitsubishi-kasei Institute Of Life Sciences
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Kudo Yoshihisa
Department Of Chemical Pharmacology Faculty Of Pharmaceutical Sciences Nagoya City University:(prese
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Ono Hideki
Department Of Toxicology And Pharmacology Faculty Of Pharmaceutical Sciences The University Of Tokyo
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Ono Hideki
Department Of Cardiology Ninon University Surugadai Hospital
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FUKUDA Hideomi
Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Nagoya City University
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