DETERIORATION OF SPINAL REFLEX IN QUAILS ORALLY INGESTING CLIOQUINOL
スポンサーリンク
概要
- 論文の詳細を見る
Ataxia occurred in quails on long-term oral ingestion of clioquinol (CQ). Crossed extensor reflexes and spinal reflex potentials in the normal and the treated quails were recorded. The incidence of these reflexes was reduced in quails given CQ. As long as the spinal reflexes were detected, there were no prominent differences in the profiles of the reflex potentials between the normal groups and those with ataxia. Augmentation of the reflex potentials by strychnine in the treated group was more extensive than that in the normal group. The mechanisms of action by which CQ induces ataxia are discussed.
- 公益社団法人日本薬学会の論文
著者
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Goto Masayoshi
ヘキストジャパン
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Goto Masayoshi
Department Of Toxicology And Pharmacology Faculty Of Pharmaceutical Sciences The University Of Tokyo
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FUKUDA Hideomi
Department of Pharmacology, College of Pharmacy, Nihon University
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Fukuda H
Department Of Pharmacology College Of Pharmacy Nihon University
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Fukuda Hideomi
Department Of Pharmacology College Of Pharmacy Nihon University
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Morishita Shinichi
Department of Computational Biology, Graduate School of Frontier Sciences, University of Tokyo
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Morishita Shinichi
Department Of Biotechnology Faculty Of Engineering Kyoto Sangyo University
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Morishita Shinichi
Department Of Toxicology And Pharmacology Faculty Of Pharmaceutical Sciences The University Of Tokyo
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Morishita Shinichi
Graduate School Of Frontier Sciences And Institute Of Medical Science The University Of Tokyo
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Goto M
Tenri Hospital Tenri Jpn
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FUKUDA Hideomi
Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Nagoya City University
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GOTO Masayoshi
Department of Biological Science, Research and Development Laboratories, Hoechst Japan Limited
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