A FACILE SYNTHESIS OF 2-METHOXY-4,4-DIMETHYL-2,5-CYCLOHEXADIENONE VIA 5,5-DIMETHYL-2-NITRO-1,3-CYCLOHEXADIENOL
スポンサーリンク
概要
- 論文の詳細を見る
5,5-Dimethyl-2-nitro-1,3-cyclohexadienol (I), which was prepared from 5,5-dimethyl-2-cyclohexenone (IIa), afforded 5,5-dimethyl-2-hydroxyimino-3-cyclohexenone (VIII) by reaction with diazomethane. VIII was hydrolyzed to 2-hydroxy-5,5-dimethyl-2,5-cyclohexadienone (Vb) via nitrone (X). Vb was methylated to III by treating with dimethyl sulfate. The yield of III from VIII was satisfiable.
- 公益社団法人日本薬学会の論文
- 1982-10-25
著者
-
山崎 高應
Faculty of Pharmaceutical Sciences, University of Toyama
-
山崎 高應
Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University
-
的場 勝英
Faculty Of Pharmaceutical Sciences Toyama Medical & Pharmaceutical University
-
的場 勝英
Faculty Of Pharmaceutical Sciences Osaka University
関連論文
- Synthetic Studies of Azaflavonoids. I. Studies on the Synthesis of 5-Azaflavone
- 8,13-Diazagona-1,3,5 (10)-triene-12-ones, Synthesis and Stereochemistry
- A Stereocontrolled Synthesis of (±)-Emetine and (±)-Protoemetinol by Intramolecular Michael Reaction
- Chemistry of 2-Methoxy-2,5-cyclohexadienone. V. Photochemical Rearrangement and Oxidation of 2-Methoxy-4-methyl-4-phenyl-2-cyclohexenone and 2-Methoxy-4-methyl-4-phenyl-2,5-eyclohexadienone(Organic,Chemical)
- 薬理活性志向のヘテロ環の合成研究
- Synthesis in the Diazasteroid Group. XX. Synthesis of the 5,14-Diazasteroid System(Organic,Chemical)
- チオアミド官能基の特性を利用する複素環合成
- An Efficient Total Synthesis of (±)-Epilupinine and (±)-Lupinine from a Common Quinolizidine Intermediate
- Favorskii Reaction of 2-Bromobicyclo[3.3.1]nonan-3-one
- Reaction of Aliphatic Dicarboxylic Acids with Acyl Chlorides in the Presence of Aluminum Chloride
- Ketene-S, N-acetals as Synthetic Intermediates for Heterocycles. Reaction of Ketene-S, N-acetals with Aryl Isocyanates
- Chemistry of 2-Methoxy-2,5-cyclohexadienone. IV. Photochemistry of 2-Methoxy-4,4-diphenyl-2,5-cyclohexadienone and 4-Dichloromethyl-2-methoxy-4-methyl-2,5-cyclohexadienone
- Reduction of Vinylogous Thioesters with Lithium Aluminum Hydride. II. Reduction of 2-Methyl-3-phenylthio-5-substituted-2-cyclopentenones
- Reduction of Vinylogous Thioesters with Lithium Aluminum Hydride. I. Reduction of β-Phenylthio-α, β-unsaturated Cyclic Ketones
- Chemistry of 2-Methoxy-2,5-cyclohexadienones. III. Syntheses of 2-Methoxy-4,4-diphenyl-2,5-cyclohexadienone and 4-Dichloromethyl-2-methoxy-4-methyl-2,5-cyclohexadienone
- Structural Modification of Bioactive Compounds. II. Syntheses of Aminophosphonoic Acids
- Chemistry of 2-Methoxy-2,5-cyclohexadienones. II. Oxidation of 2-Methoxy-4,4-dimethyl-2,5-cyclohexadienone
- Synthesis in the Diazasteroid Group. XXI. An Alternative Synthesis of the 8,16-Diazasteroid System
- KETENE-S, N-ACETALS AS SYNTHETIC INTERMEDIATES FOR HETEROCYCLES. A NOVEL SYNTHESIS OF POLYFUNCTIONALIZED PYRIDINE-2-THIONES
- Structural Modification of Bioactive Compounds. I. Syntheses of Vitamin D Analogues I
- Nitration of 2-Cyclohexenone Derivatives and Some Reactions of the Products
- AN EASY SYNTHESIS OF MONOMETHYL MALONATE DERIVATIVES
- Activated Lactams. VI. The Cycloaddition Reaction of Cyclic Ketene-S, N-acetals with Dimethyl Acetylenedicarboxylate
- Studies on the Alkaloids of Menispermaceous Plants. CCLIX. Alkaloids of Menispermum dauricum DC. (Suppl. 7). Structures of Acutumine and Acutumidine, Chlorine-Containing Alkaloids with a Novel Skeleton
- The Chemistry of Lactim Ethers. II. Reaction of Lactim Ethers with 2-Carbethoxymethyl Piperidines
- 水素化リチウムアルミニウムによるVinylogous Esterの還元(第2報)
- 水素化リチウムアルミニウムによるVinylogous Esterの還元(第1報)
- オオツヅラフジSinomenium acutum REHD.et WILS.微量成分の検索
- 1,4,7-Dioxaselenocines from 1,3-Oxaselenoles(Organic,Chemical)
- Acid-catalyzed Cyclization of Chalcones derived from Various Nitrogenous Heteroaromatic Compounds. II
- SYNTHESES OF VITAMIN D ANALOGUES 1
- Chemistry of 2-Methoxy-2,5-cyclohexadienones. I. Photochemistry of 2-Methoxy-4,4-dimethyl-2,5-cyclohexadienone
- A FACILE SYNTHESIS OF 2-METHOXY-4,4-DIMETHYL-2,5-CYCLOHEXADIENONE VIA 5,5-DIMETHYL-2-NITRO-1,3-CYCLOHEXADIENOL
- Michael Addition of [1H] Pyrrole
- Synthesis in the Diazasteroid Group. XIX. Synthesis of the 9,13-Diazasteroid System
- The Chemistry of Lactim Ethers. V. Reaction of Lactim Thioethers with β-Aminoesters
- Acid-catalyzed Cyclization of Chalcones derived from Various Nitrogenous Heteroaromatic Compounds
- A Convenient Synthesis of Monocyclic β-Lactams by Means of Solid-Liquid Phase Transfer Reactions
- Synthesis in the Diazasteroid Group. XV. Syntheses of the 5,9- and 8,13-Diazasteroids
- Synthesis in the Diazasteroid Group. XIV. Synthesis of the 13,15-Diazasteroid System
- Reaction of Lactim Thioethers with 1-Carbethoxymethyl-1,2,3,4-tetrahydroisoquinoline
- Synthesis of 8,10-Diaza-estrane
- Synthetic Studies of Azaflavonoids. II. Synthesis of 6-Azaflavonoids
- Studies on O-Alkylated Imides. II. Some Reactions of O-Ethyl Succinimide and O-Ethyl 4,4-Dimethyl-glutarimide
- Reduction of O-Alkylated Imides
- Synthesis of Zwitterionic Pyridazine Derivatives. I
- Synthesis in the Diazasteroid Group. XVIII. Syntheses of the 9,17-Diazasteroid System
- Synthesis in the Diazasteroid Group. XVII. Syntheses of the 4,11-Diazasteroid System
- Reaction of Vinylogous Esters with Grignard Reagent
- Synthesis in the Diazasteroid Group. IV. A Synthesis of 2,3-Dimethoxy-8,14-diaza-15-oxo-gona-1,3,5 (10)-triene
- 水素化リチゥムアルミニゥムによるVinylogous Esterの還元(第7報) : α-Alkoxyl基置換6員環Vinylogous Esterに関して
- 水素化リチウムアルミニウムによるVinylogous Esterの還元(第6報)
- 水素化リチウムアルミニウムによるVinylogous Esterの還元(第5報)
- 水素化リチウムアルミニウムによるVinylogous Esterの還元(第4報)
- Vinylogous Esterの接触還元(第1報)
- 水素化リチウムアルミニウムによるVinylogous Esterの還元(第3報)
- チオアミド官能基の特性を利用する複素環合成