The Chemistry of Lactim Ethers. V. Reaction of Lactim Thioethers with β-Aminoesters

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概要

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• Reaction of a cyclic β-aminoester such as 2-ethoxycarbonylmethylpiperidine (5) with the lactim thioethers 1b and 1c gave a 10-membered cyclic diamide (7) and an 11-membered ring compound (9), respectively. On the other hand, though acyclic β-aminoesters (6) reacted with 1 to afford methyl 3-methylthiopropionate (11), N-alkyl 3-methylthiopropionamide (12), lactams (13), and amidines (14), no cyclic diamide was obtained.

• 公益社団法人日本薬学会の論文
• 1981-09-25

著者

• 山崎 高應

  Faculty of Pharmaceutical Sciences, University of Toyama

• 高畑 廣紀

  富山医科薬科大学薬学部

• 山崎 高應

  Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University

• 高畑 廣紀

  Faculty of Pharmaceutical Sciences Toyama Medical and Pharmaceutical University

• 富口 明

  Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University

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