A Convenient Synthesis of Monocyclic β-Lactams by Means of Solid-Liquid Phase Transfer Reactions

スポンサーリンク

概要

• 論文の詳細を見る

• The intramolecular N-alkylation of β-bromopropionamides (1) under phase transfer conditions afforded monocyclic N-substituted β-lactams (2) in high yields. In a similar manner, cyclization by N_1-C_4 bond formation gave 4-benzoyl-2-azetidinones (4) from 3-benzoyl-3-bromopropionanilides (3).

• 公益社団法人日本薬学会の論文
• 1981-04-25

著者

• 高畑 廣紀

  富山医科薬科大学薬学部

• 山崎 高應

  Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University

• 高畑 廣紀

  Faculty of Pharmaceutical Sciences Toyama Medical and Pharmaceutical University

• 大西 義章

  Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University

• 竹原 広幸

  Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University

• 釣谷 和子

  Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University

• 竹原 広幸

  Research Laboratories, Morishita Pharmaceutical Co., Ltd.,

• 大西 義章

  Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University

• 釣谷 和子

  Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University

• 竹原 広幸

  Research Laboratories Morishita Pharmaceutical Co. Ltd.

関連論文

• Synthetic Studies of Azaflavonoids. I. Studies on the Synthesis of 5-Azaflavone
• 8,13-Diazagona-1,3,5 (10)-triene-12-ones, Synthesis and Stereochemistry
• A Stereocontrolled Synthesis of (±)-Emetine and (±)-Protoemetinol by Intramolecular Michael Reaction
• Chemistry of 2-Methoxy-2,5-cyclohexadienone. V. Photochemical Rearrangement and Oxidation of 2-Methoxy-4-methyl-4-phenyl-2-cyclohexenone and 2-Methoxy-4-methyl-4-phenyl-2,5-eyclohexadienone(Organic,Chemical)
• 薬理活性志向のヘテロ環の合成研究
• Synthesis in the Diazasteroid Group. XX. Synthesis of the 5,14-Diazasteroid System(Organic,Chemical)
• チオアミド官能基の特性を利用する複素環合成
• An Efficient Total Synthesis of (±)-Epilupinine and (±)-Lupinine from a Common Quinolizidine Intermediate
• Favorskii Reaction of 2-Bromobicyclo[3.3.1]nonan-3-one
• Reaction of Aliphatic Dicarboxylic Acids with Acyl Chlorides in the Presence of Aluminum Chloride
• Ketene-S, N-acetals as Synthetic Intermediates for Heterocycles. Reaction of Ketene-S, N-acetals with Aryl Isocyanates
• Chemistry of 2-Methoxy-2,5-cyclohexadienone. IV. Photochemistry of 2-Methoxy-4,4-diphenyl-2,5-cyclohexadienone and 4-Dichloromethyl-2-methoxy-4-methyl-2,5-cyclohexadienone
• Reduction of Vinylogous Thioesters with Lithium Aluminum Hydride. II. Reduction of 2-Methyl-3-phenylthio-5-substituted-2-cyclopentenones
• Reduction of Vinylogous Thioesters with Lithium Aluminum Hydride. I. Reduction of β-Phenylthio-α, β-unsaturated Cyclic Ketones
• Chemistry of 2-Methoxy-2,5-cyclohexadienones. III. Syntheses of 2-Methoxy-4,4-diphenyl-2,5-cyclohexadienone and 4-Dichloromethyl-2-methoxy-4-methyl-2,5-cyclohexadienone
• Structural Modification of Bioactive Compounds. II. Syntheses of Aminophosphonoic Acids
• Chemistry of 2-Methoxy-2,5-cyclohexadienones. II. Oxidation of 2-Methoxy-4,4-dimethyl-2,5-cyclohexadienone
• Synthesis in the Diazasteroid Group. XXI. An Alternative Synthesis of the 8,16-Diazasteroid System
• KETENE-S, N-ACETALS AS SYNTHETIC INTERMEDIATES FOR HETEROCYCLES. A NOVEL SYNTHESIS OF POLYFUNCTIONALIZED PYRIDINE-2-THIONES
• Structural Modification of Bioactive Compounds. I. Syntheses of Vitamin D Analogues I
• Nitration of 2-Cyclohexenone Derivatives and Some Reactions of the Products
• AN EASY SYNTHESIS OF MONOMETHYL MALONATE DERIVATIVES
• Activated Lactams. VI. The Cycloaddition Reaction of Cyclic Ketene-S, N-acetals with Dimethyl Acetylenedicarboxylate
• The Chemistry of Lactim Ethers. IV. Syntheses of 1,9-and 5,9-Diazasteroid Systems
• The Chemistry of Lactim Ethers. II. Reaction of Lactim Ethers with 2-Carbethoxymethyl Piperidines
• Acid-catalyzed Cyclization of Chalcones derived from Various Nitrogenous Heteroaromatic Compounds. II
• Chemistry of 2-Methoxy-2,5-cyclohexadienones. I. Photochemistry of 2-Methoxy-4,4-dimethyl-2,5-cyclohexadienone
• A FACILE SYNTHESIS OF 2-METHOXY-4,4-DIMETHYL-2,5-CYCLOHEXADIENONE VIA 5,5-DIMETHYL-2-NITRO-1,3-CYCLOHEXADIENOL
• Michael Addition of [1H] Pyrrole
• Synthesis in the Diazasteroid Group. XIX. Synthesis of the 9,13-Diazasteroid System
• The Chemistry of Lactim Ethers. V. Reaction of Lactim Thioethers with β-Aminoesters
• Acid-catalyzed Cyclization of Chalcones derived from Various Nitrogenous Heteroaromatic Compounds
• A Convenient Synthesis of Monocyclic β-Lactams by Means of Solid-Liquid Phase Transfer Reactions
• Synthesis in the Diazasteroid Group. XV. Syntheses of the 5,9- and 8,13-Diazasteroids
• Synthesis in the Diazasteroid Group. XIV. Synthesis of the 13,15-Diazasteroid System
• Reaction of Lactim Thioethers with 1-Carbethoxymethyl-1,2,3,4-tetrahydroisoquinoline
• Synthesis of 8,10-Diaza-estrane
• Synthetic Studies of Azaflavonoids. II. Synthesis of 6-Azaflavonoids
• Studies on O-Alkylated Imides. II. Some Reactions of O-Ethyl Succinimide and O-Ethyl 4,4-Dimethyl-glutarimide
• Reduction of O-Alkylated Imides
• Synthesis of Zwitterionic Pyridazine Derivatives. I
• Synthesis in the Diazasteroid Group. XVIII. Syntheses of the 9,17-Diazasteroid System
• Studies on Antiallergy Agents. III. Synthesis of 2-Anilino-1,6-dihydro-6-oxo-5-pyrimidinecarboxylic Acids and Related Compounds
• Synthesis in the Diazasteroid Group. XVII. Syntheses of the 4,11-Diazasteroid System
• チオアミド官能基の特性を利用する複素環合成
• 二重不斉化反応による光学純度累進効果を活用する有機合成
• 非キラルなクロマトグラフィーにおける光学分割現象
• 高選択的なヘテロ環化反応の開発と生物活性物質の合成への応用
• 2級アリルアルコールに対する分子内アミノ付加反応を基盤とする含窒素生物活性物質のキラル合成
• ELECTROPHILIC OLEFIN HETEROCYCLIZATION IN ORGANIC SYNTHESIS. : STEREOSELECTIVE INTRAMOLECULAR AMIDOMERCURATION OF γ-HYDROXY-δ, ε-UNSATURATED URETHANES

もっと見る 閉じる

スポンサーリンク