AN EASY SYNTHESIS OF MONOMETHYL MALONATE DERIVATIVES

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概要

• 論文の詳細を見る

• Monomethyl malonates (IIIa-c and Va) were synthesized from Meldrum's acid (Ia) by treating with an excess of diazomethane in the corresponding alcohols and piperidine, respectively, in quantitative yields. In a similar manner, 5-p-chlorobenzyl Meldrum's acid (Ib) afforded the corresponding monomethyl malonate derivatives (IIIe, f, and Vb). The mechanism proposed for this reaction is described.

• 社団法人日本薬学会の論文
• 1983-08-25

著者

• 山崎 高應

  Faculty of Pharmaceutical Sciences, University of Toyama

• 山崎 高広

  富山医科薬科大学

• 山崎 高應

  Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University

• 的場 勝英

  Faculty Of Pharmaceutical Sciences Toyama Medical & Pharmaceutical University

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