Structural Modification of Bioactive Compounds. I. Syntheses of Vitamin D Analogues I

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概要

• 論文の詳細を見る

• Three vitamin D analogues, (25R)-9,10-seco-spirosta-5,7,10 (19)-trien-3β-ol (I), 17β (N-methyl-N-4-methylpentylamino)-9,10-seco-androsta-5,7,10 (19)-trien-3β-ol (II), and (20S)-20-iso-pentylamino-9,10-seco-pregna-5,7,10 (19)-trien-3β-ol (III), were prepared starting from diosgenin (IVa), 3β-hydroxy-5-androsten-17-one (Va), and 3β-hydroxy-5-pregnen-20-one (VIa), respectively, via the adducts of the corresponding 5,7-dienes and 4-phenyl-1,2,4-triazoline-3,5-dione.

• 社団法人日本薬学会の論文
• 1984-04-25

著者

• 山崎 高應

  Faculty of Pharmaceutical Sciences, University of Toyama

• 的場 勝英

  Faculty of Pharmaceutical Sciences, University of Toyama

• 山崎 高広

  富山医科薬科大学

• 山崎 高應

  Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University

• 近藤 覚也

  Faculty of Pharmaceutical Sciences, Toyama Medical & Pharmaceutical University

• 的場 勝英

  Faculty Of Pharmaceutical Sciences Toyama Medical & Pharmaceutical University

• 的場 勝英

  Faculty Of Pharmaceutical Sciences Osaka University

• 近藤 覚也

  Faculty Of Pharmaceutical Sciences Toyama Medical & Pharmaceutical University

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