New Methods and Reagents in Organic Synthesis. 18. Homologation of Ketones with Trimethylsilyldiazomethane (TMSCHN_2)
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概要
- 論文の詳細を見る
Trimethylsilyldiazomethane (TMSCHN_2) easily reacts with various ketones in the presence of boron trifluoride etherate in methylene chloride solution to give chain- or ring-homologated ketones, and can be used as a stable and safe substitute for hazardous diazomethane. The reaction proceeds below 0℃ during 1-4h, and permits much more efficient homologation than can be achieved with diazomethane.
- 社団法人日本薬学会の論文
- 1982-01-25
著者
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塩入 孝之
Faculty of Pharmaceutical Sciences, Nagoya City University
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橋本 典夫
Faculty Of Pharmaceutical Sciences Nagoya City University
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塩入 孝之
名城大学薬学部
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塩入 孝之
Faculty Of Pharmaceutical Sciences Nagoya City University
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青山 豊彦
Faculty of Pharmaceutical Sciences, Nagoya City University
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青山 豊彦
名古屋市立大学大学院薬学研究科
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青山 豊彦
Faculty Of Pharmaceutical Sciences Nagoya City University
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