Eight Novel Sterols from the Roots of Bryonia dioica JACQ.

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概要

• 論文の詳細を見る

• Eight novel sterols, 4,4-dimethyl-5α-poriferasta-7,25-dien-3β-ol, (24E)-24-ethyl-29-nor-5α-lanosta-7,24(24^1)-dien-3β-ol, (24E)-24-ethyl-29-nor-5α-lanosta-9(11), 24(24^1)-dien-3β-ol, (24E)-24-ethyl-29-nor-5α-lanosta-7,9(11), 24(24^1)-trien-3β-ol, (22E, 24Z)-5α-stigmasta-7,22,24(24^1)-trien-3β-ol, 5α-stigmasta-7,9(11)-dien-3β-ol, (24E)-5α-stigmasta-7,9(11), 24(24^1)-trien-3β-ol, and (24E)-14α-methyl-5α-stigmasta-7,24(24^1)-dien-3β-ol, were isolated (as acetates) from the saponified neutral fraction of Bryonia dioica root extract. The structures were determined by spectroscopic methods. The compounds are new because the 4,4-dimethy-Δ^7-cholestene-, 4α, 14α-dimethyl-Δ^7-cholestene (or 29-nor-Δ^7-lanostene)-, and 14α-methyl-Δ^7-cholestene-skeletons and the (22E, 24Z)-Δ^<22,24(24^1)>-stigmastadiene side chain have not been found before in nature. Abundances are given of fifty three identified triterpene alcohols and sterols.

• 公益社団法人日本薬学会の論文
• 1996-06-15

著者

• KOKKE Wilhelmus

  Zynaxis Cell Science, Inc.,

• Akihisa Toshihiro

  College of Science and Technology, Nihon University

• Kimura Y

  Coll. Of Pharmacy Nihon Univ.

• Kimura Yumiko

  College Of Pharmacy Nihon University

• Yasukawa Ken

  Coll. Of Pharmacy Nihon Univ.

• Akihisa Toshihiro

  College Of Science And Technology Nihon University

• Tai Takaaki

  Morishita Jintan Co. Ltd.

• Tamura T

  Department Of Chemistry And Chemical Engineering Faculty Of Engineering Yamagata University

• TAMURA Toshitake

  College of Science and Technology, Nihon University

• ITOH Takashi

  College of Science and Technology, Nihon University

• Kokke W

  Zynaxis Inc.

• Itoh Takashi

  College Of Science And Technology Nihon University

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