Furo [3,2-b] indole Derivatives. II. Synthesis and Analgesic and Anti-inflammatory Activities of 4-Alkoxycarbonyl-2-morpholinocarbonylfuro [3,2-b] indole Derivatives
スポンサーリンク
概要
- 論文の詳細を見る
As part of a series of studies on furo [3,2-b] indole derivatives, 4-alkoxycarbonyl-2-morpholinocarbonylfuro [3,2-b] indole derivatives were synthesized, and their analgesic and anti-inflammatory activities were examined using the acetic acid writhing method in mice and the carrageenin edema method in rats. Some of these derivatives, particularly 4-isopropoxycarbonyl-2-morpholinocarbonyl-6-trifluoromethylfuro [3,2-b] indole, showed pronounced pharmacological activities. The structureactivity relationships are discussed.
- 社団法人日本薬学会の論文
- 1985-12-25
著者
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佐藤 正和
成均館大学校
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佐藤 正和
大正製薬
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川島 豊
Research Center, Taisho Pharmaceutical Co., Ltd.
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奥山 茂
Research Center, Taisho Pharmaceutical Co., Ltd.
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佐藤 正和
Research Center, Taisho Pharmaceutical Co., Ltd.
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天沼 二三雄
Research Center, Taisho Pharmaceutical Co., Ltd.
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中嶋 由茂元
Research Center, Taisho Pharmaceutical Co., Ltd.
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中嶋 由茂元
Research Center Taisho Pharmaceutical Co. Ltd.
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曽田 馨
Research Center, Taisho Pharmaceutical Co., Ltd.
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亀山 勉
Faculty of Pharmacy, Meijo University.
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川島 豊
Research Center Taisho Pharmaceutical Co. Ltd.
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川島 豊
大正製薬・総合研
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亀山 勉
Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Meijo University
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奥山 茂
Research Center Taisho Pharmaceutical Co. Ltd.
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奥山 茂
大正製薬
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天沼 二三雄
Department of Pharmacology, Research Center, Taisho Pharmaceutical Co., Ltd.
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上山 勉
Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University
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奥山 茂
大正製薬 創薬研
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亀山 勉
Department Of Chemical Pharmacology Faculty Of Pharmaceutical Sciences Meijo University
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天沼 二三雄
Department Of Pharmacology Research Center Taisho Pharmaceutical Co. Ltd.
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天沼 二三雄
Research Center Taisho Pharmaceutical Co. Ltd.
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佐藤 正和
Research Center Taisho Pharmaceutical Co. Ltd.
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曽田 馨
Research Center Taisho Pharmaceutical Co. Ltd.
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亀山 勉
Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University
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