Studies on Antirheumatic Agents : 3-Benzoylpropionic Acid Derivatives
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概要
- 論文の詳細を見る
As part of the search for new antirheumatic agents, three types of 3-benzoylpropionic acid derivatives having a mercapto moiety in their structures were prepared, and tested for suppressing activity on adjuvant arthritis in Sprague-Dawley rats. A structure-activity relationship study showed that substitution on the phenyl ring contributed to the activity and the most favorable substituent was different in each type of derivative.
- 社団法人日本薬学会の論文
- 1988-06-25
著者
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中池 司郎
Research Center, Taisho Pharmaceutical Co., Ltd.,
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竹下 紀美代
大正製薬総合研究所
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曽田 馨
Research Center, Taisho Pharmaceutical Co., Ltd.
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中池 司郎
Research Center Taisho Pharmaceutical Co. Ltd.
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亀尾 一弥
Research Center, Taisho Pharmaceutical Co., Ltd.,
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小河 邦雄
Research Center, Taisho Pharmaceutical Co., Ltd.,
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竹下 紀美代
Research Center, Taisho Pharmaceutical Co., Ltd.,
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富沢 一雪
Research Center, Taisho Pharmaceutical Co., Ltd.,
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冨沢 一雪
Research Center Taisho Pharmaceutical Co. Ltd.
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小河 邦雄
Research Center Taisho Pharmaceutical Co. Ltd.
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亀尾 一弥
Research Center Taisho Pharmaceutical Co. Ltd.
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富沢 一雪
Research Center Taisho Pharmaceutical Co. Ltd.
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曽田 馨
Research Center Taisho Pharmaceutical Co. Ltd.
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中池 司郎
大正製薬 総研
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