Mass Spectra of Trimethylsilyl Ethers of Dammarane-Type Ginseng-Sapogenins and Their Related Compounds
スポンサーリンク
概要
- 論文の詳細を見る
Complete trimethylsilylation of 20 (S)-protopanaxadiol (11), 20 (S)-protopanaxatriol (12) (Ginseng-sapogenins) and dammarenediol-II (13) was furnished by the action of trimethylsilylimidazole. The mass spectra of the pertrimethylsilyl ethers of 11,12,and 13 (TMSi-11,-12,and -13) exhibited characteristic fragmentations around their C-20,which were diagnostic for structure determination of triterpenes of this type. The mass spectra of TMSi-ethers of the deuterated compounds of 11 (11-d_2 and -d_5) demonstrated that no 1,2-elimination of TMSiOH at C-3 and -12 was involved in the fragmentation. With reference to the reports of the mass spectrometry of TMSi-oligosaccharides, the mass spectra of Ginseng saponins (ginsenosides-Rb_1 (1), -Rb_2 (2), -Rc (3), -Rd (4), -Re (5), -Rf (6), -Rg_1 (7), and -Rg_2 (8) were also studied, the results of which were found to be useful for identification and structure determination of oligoglycosides of this type.
- 公益社団法人日本薬学会の論文
- 1977-12-25
著者
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庄司 順三
School of Pharmaceutical Sciences, Showa University
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田中 治
Institute of Pharmaceutical Sciences, Hiroshima University, School of Medicine
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庄司 順三
School Of Pharmaceutical Sciences Showa University
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真田 修一
School Of Pharmaceutical Sciences Showa University Hatanodai
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田中 治
Institute Of Pharmaceutical Sciences Hiroshima University School Of Medicine
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