Reticuloendothelial System-Activating Polysaccharides from Rhizomes of Panax japonicus. : I. Tochibanan-A and -B

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概要

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• From rhizomes of Panax japonicus (Araliaceae), two polysaccharides named tochibanan-A and -B, which show reticuloendothelial-potentiating activity in the carbon clearance test in mice, were isolated. The structure of tochibanan-A (molecular mass : 23000) was elucidated as a linear β-1,4-D-galactan. Tochibanan-B (molecular mass : 40000) consists of D-galactose (87.1%), L-arabinose, D-glucose and D-galacturonic acid and has a β-D-(1→4)-linked galactopyranosyl backbone possessing GalA-(1→6)-Gal, Ara-(1→5)-Ara, Gal, and Glc side chains. The structure around the branching points and the repeating unit were investigated and a possible structure of tochibanan-B is proposed.

• 社団法人日本薬学会の論文
• 1989-10-25

著者

• 水谷 健二

  丸善製薬

• 笠井 良次

  Institute of Pharmaceutical Sciences, Hiroshima University, School of Medicine

• 田中 治

  Institute of Pharmaceutical Sciences, Hiroshima University, School of Medicine

• 田中 治

  広島大

• 大谷 和弘

  広島大・医

• 笠井 良次

  広島大・医

• 大谷 和弘

  Institute of Pharmaceutical Sciences, Hiroshima University

• 鳩野 俊三

  Central Research Laboratories, Wakunaga Pharmaceutical Co., Ltd.,

• 水谷 健二

  Institute of Pharmaceutical Sciences, Hiroshima University School of Medicine

• 田中 治

  Institute Of Pharmaceutical Sciences Hiroshima University School Of Medicine

• 鳩野 俊三

  Central Research Laboratories Wakunaga Pharmaceutical Co. Ltd.

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