Syntheses of N-Acyl Derivatives of α-Methyl-3,4-methylenedioxyphenethylamine and their Analgesic Activity.
スポンサーリンク
概要
- 論文の詳細を見る
Several acids- and aminoacids-derivatives of α-methyl-3,4-methylenedioxyphenethylamine were synthesized and their analgesic activities in mice were estimated by two methods. The most potent compound was propionamide of the amine (SA-8) and this was 1.4 times more potent than aminopyrine. SA-8 was sedative in mice, and it markedly augmented the hypnotic action of hexobarbital.
- 社団法人日本薬学会の論文
- 1963-05-25
著者
-
粕谷 豊
Faculty of Pharmaceutical Sciences, University of Tokyo
-
渡辺 稔
Faculty of Pharmaceutical Sciences, University of Tokyo
-
高木 敬次郎
Faculty of Pharmaceutical Sciences, University of Tokyo
-
藤江 恭
Faculty of Pharmaceutical Sciences, University of Tokyo
-
萱岡 節子
Faculty of Pharmaceutical Sciences, University of Tokyo
-
高木 敬次郎
Department Of Pharmacotherapeutics Faculty Of Pharmaceutical Sciences Science University Of Tokyo
-
藤江 恭
Faculty Of Pharmaceutical Sciences University Of Tokyo
-
粕谷 豊
東京大学薬学部
-
萱岡 節子
東京大学薬学部
-
渡辺 稔
Department of Toxicology and Pharmacology, Faculty of Pharmaceutical Sciences, The University of Tokyo
関連論文
- Studies on a New Beta-adrenoceptor Blocker, 6-(2-Hydroxy-3-isopropylamino) propoxy Benzothiazole Succinate (KF-577)
- クロロキン眼障害の実験的研究 (第一回毒作用研究会記事)
- 小動物の行動に対する薬物作用の研究(第1報) : 中枢興奮薬およびそれらの併用効果について
- Syntheses of 1-Dimethoxy-phenyl-3-alkylaminobutanols.I.
- Experimental Study on the Pharmacology of N-(α-Methyl-3,4-methylenedioxyphenethyl) propionamide.
- Syntheses of N-Acyl Derivatives of α-Methyl-3,4-methylenedioxyphenethylamine and their Analgesic Activity.
- Synthesis of Piperidine Derivatives with a Quinazoline Ring System as Potential Antihypertensive Agents
- Spiropiperidines. I. Synthesis of 1'-Substituted Spiro [4H-3,1-benzoxazine-4,4'-piperidin]-2 (1H)-one Derivatives and Evaluation of Their Antihypertensive Activity
- 鎮痙作用の薬品作用学的研究;アセチルコリンに対する競合的並びに非競合的拮抗について
- 抗ペプシン薬, Sulfated Glyptide(GLPS), および制酸薬, 重炭酸ナトリウムの抗Shay潰瘍作用, 抗ペプシン作用, 制酸作用に関する研究
- Effects of Crude Platycodin on Gastric Secretion and Experimental Ulcerations in Rats
- Synthesis of 1-and 3-(1-Substituted 4-Piperidinyl)-1,2,3,4-tetrahydro-2-oxoquinazolines as Potential Antihypertensive Agents
- Pharmacological Studies of Panacis Japonici Rhizoma. II
- Pharmacological Studies of Panacis Japonici Rhizoma. I
- Pharmacobiodynamics
- Effect of Terephthalic Acid on the Blood Level of Sulfaethylthiadiazole.
- Atropine-like Activities of 2-Substituted 5-Piperidinomethylfuran Derivatives
- 日本薬学会学術賞紹介 : -1 辰野高司, 上野芳夫両氏の業績
- Studies on the Drugs for Peptic Ulcer. A Reliable Method for Producing Stress Ulcer in Rats.
- Studies on the Drugs for Peptic Ulcer. Pharmacological Studies on the Effects of Synthetic Antispasmodics mixed with Antacid.
- Syntheses of Bradykinin Analogs Containing Sarcosine Residues and Their Biological Activities
- マウスにおける薬物の脳室内注入法
- モノアミン酸化酵素阻害剤の研究(第3報) : 直鎖脂肪族1級アルコールおよびアミンの作用
- モノアミン酸化酵素阻害剤の研究(第2報) : Phenethylamine誘導体の作用
- Preparation of Tyrosol and 4-Methoxyphenethyl Alcohol.
- 芍薬の薬理学的研究(第3報) : ペオニフロリンの循環呼吸器系および摘出臓器におよぼす作用
- 芍薬の薬理学的研究(第2報) : ペオニフロリンの抗炎症作用, 胃液分泌抑制作用, ストレス潰瘍予防作用, 抗利尿作用および甘草成分FM100との併用効果
- 芍薬の薬理学的研究(第1報) : ペオニフロリンの中枢作用および甘草成分FM100との併用効果
- 薬効と毒性における3種解熱鎮痛薬の配合効果について
- Coronary Vasodilating Effect of Some Chromanone Derivatives
- 桔梗の薬理学的研究(第3報)粗Platycodinの呼吸循環器系におよぼす作用およびその他の薬理作用
- 桔梗の薬理学的研究(第2報)粗Platycodinの抗炎症作用, 摘出臓器におよぼす作用およびその他の薬理作用
- 桔梗の薬理学的研究(第1報)粗Platycodinの毒性および中枢抑制作用
- Chemicopharmacological Studies on Antispasmodic Action. XV. Non-specific Antispasmodic Action on Tracheal Muscle.
- Changes in Catecholamine Levels of Mouse Brain during Oscillation-stress
- Anti-inflammatory Activities of Hederagenin and Crude Saponin isolated from Sapindus mukorossi GAERTN
- Effects of Some Vasoactive Agents on Isolated Blood Vessels from Cholesterol-fed Rabbits
- Vasodilating Effect of Diphenylalkanolamines in Anesthetized Dogs
- Cardiovascular Effects of Some Peptide Analogues consisting of Cystine and/or Tyrosine
- Studies on Analgesics. IV. A Recording Apparatus for Pain Reaction on the Hot Plate.
- 薬学教育の立場から(生薬学の現状と将来)
- 臨床薬学をめぐる用語の整理
- 幻でなくなった臨床薬学(臨床薬学の現状をいかにとらえるか)
- 薬学と病院薬剤師
- Clonixinの薬理学的研究(第1報) : 抗炎症,鎮痛作用と消化器に対する作用
- EFFECT OF CALCIUM IONS AND PHOSPHOLIPIDS ON ANTIACETYLCHOLINE ACTION OF ACETONE AND PAPAVERINE
- 柴胡の薬理学的研究(第2報) : Crude Saikosidesの抗炎症その他の薬理作用
- 柴胡の薬理学的研究(第1報) : Crude Saikosidesの毒性ならびに中枢抑制作用
- ACTIONS OF DOPAMINE AND ITS DERIVATIVES ON THE TAENIA CAECUM AND TRACHEAL MUSCLE FROM THE GUINEA PIG AND THE VAS DEFERENS FROM THE RAT
- THE EFFECT OF PROPRANOLOL ON THE STRESS AND SHAY ULCERATIONS IN RATS
- 中枢興奮薬の脳室内投与と動物の行動
- PHARMACOLOGICAL EXPERIMENTS WITH THE ISOLATED EXTRAOCULAR MUSCLE FROM RABBIT
- EFFECTS OF SUBCELLULAR FRACTIONS OF THE DOG SMALL INTESTINAL SMOOTH MUSCLE ON ACETYLCHOLINE-INDUCED CONTRACTION OF GLYCEROL EXTRACTED SKELETAL MUSCLE
- PURIFICATION OF HISTAMINE RECEPTOR IN CAT SMALL INTESTINAL MUSCLE : I) SPECIFICITY OF LABELING HISTAMINE RECEPTOR WITH RADIOACTIVE DIBENAMINE
- ラット胃の慢性的自律神経切断による薬物反応性の変化について
- シロネズミ脳波の覚醒反応に対する向精神薬とくに静穏薬の作用について
- 鎮痙剤の化学構造とその作用
- ビタミンB_1およびその誘導体の抗炎症作用(第1報)
- 1-〔2-{α-(p-Chlorophenyl)-benzyloxy}ethyl〕piperidine(HT-11)の鎮咳効果の作用点の追究
- A New View on the Site of Action of Pilocarpine and Arecoline in the Isolated Guinea Pig Ileum.
- Chemicopharmacological Studies on Antispasmodic Action. IX. Precise Discrimination of Atropine-like Activity and Papaverine-like Activity as Competitive and Non-competitive Antagonism to Acetylcholine.
- Chemicopharmacological Studies on Antispasmodic Action. VII. Antagonism to Acetylcholine tested with Rectus Abdominis of Frog.
- タイトル無し
- タイトル無し
- タイトル無し