Syntheses of 1-Dimethoxy-phenyl-3-alkylaminobutanols.I.
スポンサーリンク
概要
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The 1-derivatives of 1-(2,5-dimethoxyphenyl)-3-alkylaminobutanols (III) were synthesized in order to investigate their pharmacological action. 2', 5'-Dimethoxycrotonophenone (I) which was prepared from hydroquinone dimethylether and crotonyl chloride by the Friedel-Crafts reaction, was reacted with various aliphatic amines to form 2-alkylamino-2', 5'-dimethoxy-propiophenone (II). Compounds (III) were obtained by the reaction of II with various Grignard's reagents.
- 社団法人日本薬学会の論文
- 1967-04-25
著者
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粕谷 豊
Faculty of Pharmaceutical Sciences, University of Tokyo
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渡辺 稔
Faculty of Pharmaceutical Sciences, University of Tokyo
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金井 義雄
Oji Pharmaceutical Works, Nippon Kayaku Co., Ltd.
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浜野 弘明
Oji Pharmaceutical Works, Nippon Kayaku Co., Ltd.
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粕谷 豊
東京大学薬学部
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浜野 弘明
Oji Pharmaceutical Works Nippon Kayaku Co. Ltd.
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金井 義雄
Oji Pharmaceutical Works Nippon Kayaku Co. Ltd.
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渡辺 稔
Department of Toxicology and Pharmacology, Faculty of Pharmaceutical Sciences, The University of Tokyo
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