Studies on the "Signal" Constituents for the Evaluation of Animal Crude Drugs. III. Nucleic Acid Components
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概要
- 論文の詳細を見る
An analytical method for determining the contents of 7 nucleic acid bases, 6 ribonucleosides and 5 deoxyribonucleosides in animal crude drugs were established. The contents in free nucleic acid components (the ice-cold extracts) and in total nucleic acid components (the heated extracts) of 8 crude drugs were quite different from one another, indicating that these content pattrens could be used as a "signal" of each animal crude drug. For example, the contents of inosine in Lumbricus, uracil in Cervi Parvum Cornu, and guanine and hypoxanthine in Hippocampus were high. The total contents in each crude drug were about twice or three times as large as the free contents. The main degradation products by the heated extracts were adenine and guanine.These results suggested that the contents of nucleic acid components could be one of the "signal" constituents for evaluation of animal crude drugs.
- 公益社団法人日本薬学会の論文
- 1997-03-15
著者
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Nakai H
Analytical Research Laboratory Tanabe Seiyaku Co. Ltd.
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Hashimoto A
Analytical Research Laboratory Tanabe Seiyaku Co. Ltd.
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Hashimoto Akio
Analytical Research Laboratory Tanabe Seiyaku Co. Ltd.
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Nakai Hideo
Analytical Research Laboratory Tanabe Seiyaku Co. Ltd.
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Sato T
Tanabe Seiyaku Co. Ltd. Osaka Jpn
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NAKAMURA Takashi
Analytical Research Laboratory, Tanabe Seiyaku Co., Ltd.,
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KOKUSENYA Yoshio
Analytical Research Laboratory, Tanabe Seiyaku Co., Ltd.,
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SATO Tadashi
Analytical Research Laboratory, Tanabe Seiyaku Co., Ltd.,
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Nakamura T
School Of Pharmaceutical Sciences Mukogawa Women's University
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Nakamura T
Department Of Hospital Pharmacy School Of Medicine Kobe University
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Nakai H
Minase Research Institute Ono Pharmaceutical Co. Ltd.
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Kokusenya Y
Analytical Chemistry Department Product And Technology Development Laboratory Tanabe Seiyaku Co. Ltd
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Kokusenya Yoshio
Analytical Research Laboratory Tanabe Seiyaku Co. Ltd.
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Sato Tadashi
Analytical Chemistry Research Laboratory Tanabe Seiyaku Co. Ltd.
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Kokusenya Yoshio
Analytical Chemistry Department, Product and Technology Development Laboratory, Tanabe Seiyaku Co., Ltd.,
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