Accumulation of _L-Cystathionine by an Escherichia coli Mutant Deficient in Cystathionine Beta-Lyase

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概要

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• An Escherichia coli mutant deficient in cystathionine β-lyase was found to accumulate a sub-stance detectable by ninhydrin reaction and chloride platinic acid reaction in its cells (rarely in the culture supernatant) when cultured with a limited amount (50-200 μg/ml) of L-methionine to support the growth. The product was released by freezing treatment and isolated by ion-exchange chromatography (cation exchange resin: Daiaion SK1B). It was identified as _L-cystathionine by liquid chromatography-mass spectrometry, ^<13>C- and ^1H-nuclear magnetic resonance analyses and high-performance liquid chromatography (as its 2,3,4,6-tetra-O-acetyl-β-_D-glucopyranosyl isothio-cyanate derivative).

• 社団法人日本生物工学会の論文
• 2002-08-25

著者

• FURIHATA Kazuo

  Graduate School of Agricultural and Life Sciences, The University of Tokyo

• FURIHATA Kazuo

  Division of Agriculture and Agricultural Life Sciences, The University of Tokyo

• Furihata K

  Univ. Tokyo Tokyo Jpn

• Furihata Kazuo

  Graduate School Of Agricultural And Life Sciences University Of Tokyo

• Furihata Kazuo

  Department Of Applied Biological Chemistry University Of Tokyo

• Furihata Kazuo

  Division Of Agriculture And Agricultural Life Science The University Of Agriculture

• Toda K

  Univ. Tokyo Tokyo Jpn

• Toda K

  Department Of Applied Chemistry And Biotechnology Niigata Institute Of Technology

• Toda K

  Faculty Of Engineering Niigata Institute Of Technology

• Takada Y

  Faculty Of Pharmaceutical Sciences Science University Of Tokyo

• Takahashi Yoko

  Kitasato Institute For Life Sciences Kitasato University

• Furihata Kazuo

  Division Of Agriculture And Agricultural Life Sciences

• Onodera Masayuki

  Department Of Biosystem Science Graduate School Of Science And Technology Niigata University

• Onodera Masayuki

  Faculty Of Engineering Niigata Institute Of Technology

• TANAKA Yoshitake

  Research Center for Biological Function

• Tayama Kenji

  Nakano Biochemical Research Institute Nakano Vinegar Co. Ltd.

• NISHI TAKUYA

  Graduate School of Integrated Science and Art, University of East Asia

• ARAKI KAZUMI

  Graduate School of Integrated Science and Art, University of East Asia

• TODA KIYOSHI

  Faculty of Engineering, Niigata Institute of Technology

• TANAKA KAZUHIKO

  Faculty of Engineering University of East Asia

• Tanaka Y

  Faculty Of Pharmaceutical Sciences Science University Of Tokyo

• Furukawa Kensuke

  Graduate School Of Bioresource And Bioenvironmental Sciences Kyushu University

• Nishi Takuya

  Graduate School Of Integrated Science And Art University Of East Asia

• Toda Kiyoshi

  Faculty Of Engineering Niigata Institute Of Technology

• Furihata Kazuo

  Department Of Applied Biological Chemistry Graduate School Of Agriculture And Life Sciences The Univ

• Taniguchi Y

  Kitasato Institute For Life Sciences Kitasato University

• Tanaka Y

  Research Center For Biological Function

• Tanaka Y

  Research Center For Biological Function The Kitasato Institute

• Takahashi Yoko

  Graduate School Of Agricultural Science Tohoku University

• Takahashi Yoko

  The Kitasato Institute

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