DNA strand breaks induced by carbon ions near the Bragg peak-Are DSBs induced more efficiently than SSBs?

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概要

• 論文の詳細を見る
• 日本放射線影響学会の論文

著者

• YASUDA Nakahiro

  National Institute of Radiological Sciences

• Konishi Teruaki

  Dept. Technical Support And Development National Institute Of Radiological Sciences

• Higashi Akio

  Kobe Prefecture Government

• KANAI Tatsuaki

  Natl. Inst. Radiol. Sci.

• FURUSAWA Yoshiya

  Natl. Inst. Radiol. Sci.

• Sato Yukio

  National Institute Of Radiological Sciences

• FUJISAKI Takashi

  Rikkyo Univ.

• TAKEMURA Tomohiro

  Rikkyo Univ.

• HIEDA Kotaro

  Rikkyo Univ.

• YASUDA Nakahiro

  Natl. Inst. Radiol. Sci.

• SATO Yukio

  Natl. Inst. Radiol. Sci.

• YAMAGUCHI Hiroshi

  Natl. Inst. Radiol. Sci.

• YASUDA Nakahiro

  Natl Inst Radiol Sci

• Furusawa Y

  Research Center For Charged Particle Therapy National Institute Of Radiological Sciences

• YAMAGUCHI Hiroshi

  National Institute of Radiological Sciences

• Kanai Tatsuaki

  Natl. Inst. Of Radiological Sciences

• Kanai Tatsuaki

  Department Of Technical Support And Development Fundamental Technology Center National Institute Of

• Kakizaki Takehiko

  Dep. Of Radiation Oncology Gunma Univ. Graduate School Of Medicine

• Hieda Kotaro

  Rikkyo Ultiv.

関連論文

• Comparison of DNA Breaks at Entrance Channel and Bragg Peak Induced by Fast C^ Ions : Influence of the Addition of Platinum Atoms on DNA
• Two Major Factors Involved in the Reverse Dose-rate Effect for Somatic Mutation Induction are the Cell Cycle Position and LET Value
• Current status of microbeam irradiation system for mammalian cells, SPICE at NIRS
• Mass Resolution for Iron Isotopes in CR-39 Track Detector
• Responses of total and quiescent cell populations in solid tumors to carbon ion beam irradiation (290 MeV/u) in vivo
• Evaluation of Late Radiation Damage of Normal Tissues in Mouse Hind Legs after Irradiation with Carbon Beams
• RBE and Dose Distribution of Heavy Ion Beams.
• Dose response relations in acute cell death of pancreatic islets after irradiation of golden hamster with X-ray ,7OMeV proton and 290MeV carbon beams.
• RBBs of 30MeV Fast Neutrons and 135MeV Carbon Beams for Clongenecities in Mouse Growing Tail Cartilage Cells.
• The effects of cell death and mutatlon induction lrradiated with acceterated carbon ion beams with spread out Bragg peak.
• LET dependence of biological effects in normal human cells irradiated wfth accelerated neon ions.
• Protective Effects of Melatonin Against Low- and High-LET Irradiation
• Repair of Skin Damage During Fractionated Irradiation with Gamma Rays and Low-LET Carbon Ions
• Biological Gain of Carbon-ion Radiotherapy for the Early Response of Tumor Growth Delay and against Early Response of Skin Reaction in Mice
• 196 Sub-Letahl Damage Repairs Efficiently After High-LET Radiation(Physics, chemistry and DNA damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Spectra of Linear Energy Transfer vs. Relative Biological Effectiveness for Accelerated Heavier Ions upon Clonogenic Survival of V79 Cells
• RBE and OER for Cell Killing upon V79 Cells by Heavy-Ion Beams at a Very High LET Region
• Biological effects of heavy-ion irradiation on DNA double-strand breaks repair deficient mutant cell line
• Response of Crypt Cell Survivals of Mouse Intestine after Fractionated Doses of Accelerated Carbon-Ion with Spread-Out Bragg Peak.
• Analysis of Survival Curve Parameters caused by High-LET Accelerated Ion Beams, Cell Strains, and LETS
• Exploration of 'Over Kill Effect' of High-LET Ar-and Fe-ions by Evaluating the Fraction of Non-hit Cell and Interphase Death
• Radiosensitivity of Human Skin Cells in vitro to Accelerated Heavy Ions.
• Heavy-Ion Microbeam System at JAEA-Takasaki for Microbeam Biology
• Cell Irradiation System with a Single or Precise Numbers of Heavy Ions using a Collimated Heavy Ion Microbeamat TIARA, JAERI Takasaki
• Relative Biological Effectiveness of Accelerated Heavy Ions for Induction of Morphological Transformation in Syrian Hamster Embryo Cells
• Relative Biological Effectiveness of Accelerated Heavy Particles for Induction of In Vitro Transformation of Hamster Embryonic Cells.
• LET Dependence for Somatic Mutation Cross Section of Drosophila Irradiated with Heavy Ion Beams
• LET Dependence for Induction of Drosophila Somatic Mutations Irradiated with Heavy Ion Beams.
• Effects of Locally Targeted Heavy-ion and Laser Microbeam on Root Hydrotropism in Arabidopsis thaliana
• Effectiveness of Monoenergetic and Spread-Out Bragg Peak Carbon-Ions for Inactivation of Various Normal and Tumour Human Cell Lines
• Effect of Microgravity on the Cell Recovery of Escherichia coli Pre-Irradiated by Carbon Ion Beams
• Biological Intercomparison Using Gut Crypt Survivals for Proton and Carbon-Ion Beams
• Relationship between Aberration Yield and Mitotic Delay in Human Lymphocytes Exposed to 200 MeV/u Fe-ions or X-rays
• LET-Dependence of Wing-hair and Eye-color Mosaic Spots Inductions at the Somatic Cells of Drosophila Larva Irradiated with 12C (290MeV/u) Ion Beams
• A New Method for the Simultaneous Detection of Mammalian Cells and Ion Tracks on a Surface of CR-39
• Number of Fe Ion Traversals Through a Cell Nucleus for Mammalian Cell Inactivation Near the Bragg Peak
• 210 Mutation Spectrum of Bacillus subtilis Spore Irradiated With Heavy Ion Near the Bragg Peak(Physics, chemistry and DNA damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 200 Each Ion Traversal Induces a DSB Cluster in Cell Nucleus(Physics, chemistry and DNA damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Visualization of Heavy Ion Traversals in Cell Nucleus : Labeling of DNA Strand Breaks with BrdU
• DNA strand breaks and base damage induced by low energy ions near Bragg peak
• Strand breaks in pBR322 DNA in solution induced by low energy carbon ions
• DNA strand breaks induced by carbon ions near the Bragg peak-Are DSBs induced more efficiently than SSBs?
• DNA strand breaks induced by heavy ions near the Bragg peak.
• Induction of Chromatin Damage and Distribution of Isochromatid Breaks in Human Fibroblast Cells Exposed to Heavy Ions
• Analysis of Unrejoined Chromosomal Breakage in Human Fibroblast Cells Exposed to Low- and High-LET Radiation
• Radiation-Quality Dependent Bystander Effects Induced in Normal Human Fibroblasts by X-ray, Proton and Heavy-Ion Microbeams
• Microbeam Irradiation Facilities for Radiobiology in Japan and China
• Adaptive Response in Zebrafish Embryos Induced Using Microbeam Protons as Priming Dose and X-ray Photons as Challenging Dose
• RBE for scid cells irradiated with high LET radiations
• The Influence of Mutation Induction in Normal Human Fibroblasts Irradiated with X Rays and Iron Ions
• Signaling factors and pathways of targeted irradiation induced bystander responses in tumor cells
• 8^ International Workshop on Microbeam Probes of Cellular Radiation Response
• 1P452 An energy-tunable X-ray microbeam irradiation system at the Photon Factory(20. Radiation biology,Poster Session,Abstract,Meeting Program of EABS &BSJ 2006)
• Repair Kinetics of DNA-DSB Induced by X-rays or Carbon Ions under Oxic and Hypoxic Conditions
• Microbeams of Heavy Charged Particles
• Bystander Effect in Lymphoma Cells Vicinal to Irradiated Neoplastic Epithelial Cells : Nitric Oxide Is Involved
• Uptake of CDDP-containing Polymeric Micelles by Cells Using Particle Induced X-Ray Emission
• Single Cell Irradiation System at the Wakasa Wan Energy Research Center
• 235 Synchrotron X-ray Microbeam Irradiation System : 2. Performance Test by Cell Irradiation Experiments(Micro-beam irradiation, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 216 Cell Inactivation and Double Strand Breaks Induction in V79 cells by Monochromatic X rays on Phosphorus K-shell Absorption peak(Physics, chemistry and DNA damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Distribution of DNA Damage induced by high LET heavy ion particle beams
• HIMAC Carbon-12 Induced Apoptosis in Murine Leukemia Cells, L5178Y and L5178YS
• 198 LET dependence of Oxidative DNA Damage Induced by Heavy Ions under Hypoxic Condition(Physics, chemistry and DNA damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Strand Break Induction in Plasmid DNA Irradiated with Low Energy Electrons
• Studies of the Induction of Radiation Damage in DNA Using Low-Energy Photons (SR) and Electrons.
• SPICE (Single Particle Irradiation to Cell) Facility at NIRS
• Heavy-ion Induced Chromatid Break and Repair Kinetics in Normal Human Fibroblasts
• Radiation Induced Bystander Effect by Gap Junction Channels in Human Fibroblast Cells
• Signal Transfer Pathways Involved in the Irradiation-Induced Bystander Effects
• Synergistic Effect by Heavy-Ion Beams and a Hypoxic Sensitizer on Repreductive Death and Apoptosis of V79 Cells
• Detection of Oxidative DNA Damage Induced by Heavy Ions at NIRS-HIMAC
• Models for Mixed Irradiation with a 'Reciprocal-Time' Pattern of the Repair Function
• Killing, Mutation and DNA Double Strand Breaks in Mammalian Cells Induced by Monochromatic X-rays with Resonance Energy of Phosphorus K-absorption Edge
• Irradiation System of Monochromatic Ultrasoft X-Rays for Wet Biological Samples.
• Design of an Irradiation System of Monochromatic Ultrasoft X-rays for Wet Samples
• Comparison between DNA Strand Breaks and the Oxidation Yield of Ferrous Ion in a Fricke Solution Induced by Monochromatic Photons in the 2.147-10 keV Region
• Influence of the Shielding on the Induction of Chromosomal Aberrations in Human Lymphocytes Exposed to High-energy Iron Ions
• Shielding and Microdosimetric Measurement of High Energy Neutrons and LET-dependence of TLD
• Quantitative analysis of enviromental UV from the sun as well as white and fluorescent lamps using a thymidylyl-(3'-5')-thymidine act in o meter
• Lack of Interaction Between Accererated Argon Ion and X-ray Biological Damage
• Yield of DNA Strand Breaks and Base Damages Induced by Photoabsorption of Phosphorus
• Detection System for Micro-structure of Clustered Damage Induced by Auger Effects of Iodine
• Seasonal Variation of Harmful Solar UV Measured with a Thymidylyl-(3-5)-thymidine (dTpdT) Actinometer.
• Synergistic Effect by Heavy-Ion Beams and a Hypoxic Sensitizer
• Loss of the Cell Adhesive Ability and LET by Heavy-Ion Exposure
• Improvement of Mass Resolution for Iron Isotopes in CR-39 Track Detector
• Mass Resolution for Iron Isotopes in CR-39 Track Detector
• Uptake of CDDP-containing Polymeric Micelles by Cells Using Particle Induced X-Ray Emission
• Visualization of Heavy Ion Tracks by Labeling 3-OH Termini of Induced DNA Strand Breaks
• Single- and double-strand breaks induced by monochromatic ultra-soft X-rays from 60 to 550 eV.
• Biologcal dosimetry of solar UV radiation : Correlation betveen sporocidal activity and spectral irradiaace.
• Effects of ionization in K-shell of Br and in L-shell of Pt on DNA strand breaks.
• Possible Application of MEMS Micro-fabrication Technologies to Microbeam Probing Studies
• Visualization of Heavy Ion Tracks by Labeling 3'-OH Termini of Induced DNA Strand Breaks
• Estimation of Yields of OH Radicals in Water Irradiated by Ionizing Radiation
• Comparison Between the Yield of DNA Strand Breaks and Ferrous Ion Oxidation in a Fricke Solution Induced by a Heavy-Ion Beam
• Effects of FractionalIrradiation of Carbon Ions for Survival and Mutation Frequency on Mammalian Cells
• Structural Modification along Heavy Ion Tracks in Poly(allyl diglycol carbonate) Films
• Action spectra for dTpdT photoproducts in the near- and far-UV regions.
• Triphasic Low-dose Response in Zebrafish Embryos Irradiated by Microbeam Protons

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