Induction of Chromatin Damage and Distribution of Isochromatid Breaks in Human Fibroblast Cells Exposed to Heavy Ions
スポンサーリンク
概要
- 論文の詳細を見る
The frequency of chromatid breaks and the distribution of isochromatid breaks were measured in G2-phase normal human fibroblasts prematurely condensed a short time after exposure to low- or high-LET radiations. The average number of isochromatid breaks from a single particle traversal increased with increasing LET values, while the average number of chromatid-type breaks appeared to reach a plateau. The distribution of isochromatid breaks after high-LET iron particles exposure was overdispersed compared to γ-rays, indicating that a single iron particle traversal through a cell nucleus can produce multiple isochromatid breaks.
- 日本放射線影響学会の論文
著者
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Ito Hisao
Department Of Radiology Graduate School Of Medicine Chiba University
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FURUSAWA Yoshiya
Heavy-ion Radiobiology Research Group, Research Center for Charged Particle Therapy, National Instit
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KAWATA Tetsuya
Department of Radiology, Graduate School of Medicine, Chiba University
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SHIGEMATSU Naoyuki
Department of Radiology, School of Medicine, Keio University
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CUCINOTTA Francis
NASA Lyndon B Johnson Space Center, Radiation Biophysics Laboratory Houston TX
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GEORGE Kerry
NASA Lyndon B Johnson Space Center, Radiation Biophysics Laboratory Houston TX
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FURUSAWA Yoshiya
National Institute of Radiological Sciences
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FUTAMI Yasuyuki
Shizuoka Cancer Center
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Futami Yasuyuki
茨城県立医療大学 放射線技術科学科
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Futami Yasuyuki
The Institute Of Physics University Of Tsukuba
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Ueda Takuya
Department Of Radiology Stanford University School Of Medicine
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George Kerry
Nasa Lyndon B Johnson Space Center Radiation Biophysics Laboratory Houston Tx
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George Kerry
米国
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George Kerry
Nasa Lyndon B. Johnson Space Center Radiation Biophysics Laboratory
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Sanuki Naoko
大船中央病院 放射線治療室
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MOTOORI Ken
Department of Radiology, Graduate School of Medicine, Chiba University
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Ueda Takuya
Department Of Chemistry And Biotechnology Graduate School Of Engineering The University Of Tokyo
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DURANTE Marco
Dipartimento di Scienze Fisiche, Universita Federico II
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WU HONGLU
NASA Lyndon B. Johnson Space Center, Radiation Biophysics Laboratory
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Shigematsu Naoyuki
Department Of Radiology Keio University School Of Medicine
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Furusawa Y
Research Center For Charged Particle Therapy National Institute Of Radiological Sciences
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Cucinotta Francis
Nasa Lyndon B Johnson Space Center Radiation Biophysics Laboratory Houston Tx
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Motoori Ken
Department Of Radiology Graduate School Of Medicine Chiba University
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Durante Marco
Gsi Biophysics Dep. And Technical Univ. Of Darmstadt
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Durante Marco
Dipartimento Di Scienze Fisiche Universita Federico Ii:infn-sezione Di Napoli
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Sanuki Naoko
Department Of Radiology Keio University School Of Medicine
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Kawata Tetsuya
Department Of Radiology Graduate School Of Medicine Chiba University
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Kawata Tetsuya
Department Of Internal Medicine Ii Hokkaido University School Of Medicine
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Furusawa Yoshiya
Heavy-ion Radiobiology Res. Group National Inst. Of Radiological Sciences
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Ito Hisao
Department Of Radiology Chiba University School Of Medicine
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Wu Honglu
Wyle Life Sciences:nasa Johnson Space Center
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Ito Hisao
Department Of Radiology Chiba University Hospital
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Ito Hisao
Department Of Diagnostic Radiology And Respiratology Miyagi Prefectural Semine Hospital
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Furusawa Yoshiya
Heavy-ion Radiobiol. Res. Gr. Res. Center Charged Particle Therapy Nirs.
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Wu Honglu
Nasa Johnson Space Center
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Ito Hisao
Departmen Of Radiology School Of Medicine Keio University
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UEDA Takuya
Department of Agricultural Chemistry, Faculty of Agriculture, University of Tokyo
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