Biological effects of heavy-ion irradiation on DNA double-strand breaks repair deficient mutant cell line

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概要

• 論文の詳細を見る
• 日本放射線影響学会の論文

著者

• YATAGAI Fumio

  RIKEN Institute

• EGUCHI-KASAI Kiyomi

  NIRS

• Ikeda Hiroshi

  Department Of Radiation Oncology National Cancer Center Hospital East

• YATAGAI Fumio

  IPCR

• KANAI Tatsuaki

  Natl. Inst. Radiol. Sci.

• FUKUTSU Kumiko

  Natl. Inst. Radiol. Sci.

• ITSUKAICHI Hiromi

  Natl. Inst. Radiol. Sci.

• MURAKAMI Masahiro

  Natl. Inst. Radiol. Sci.

• YATAGAI Fumio

  Inst. Phy. Che. Res.

• Eguchi‐kasai K

  National Inst. Radiological Sci. Chiba Jpn

• Eguchi Kasai

  Research Center For Radiation Protection National Institute Of Radiological Sciences

• Kasai Kiyomi

  Division Of Radiobiology & Biodosimetry National Institute Of Radiological Sciences

• Eguchi-kasai Kiyomi

  Div. Rad. Haz. Natl. Inst. Radiol. Sci.

• Koike Sachiko

  Heavy-ion Radiobiology Res. Group National Inst. Of Radiological Sciences

• Murakami Masahiro

  Radiation Hazards Research Groupe Natl. Inst. Radiat Sci.

• Yatagai F

  Riken Saitama Jpn

• Yatagai Fumio

  Division Of Radioisotope Technology Riken

• Yatagai Fumio

  Inst. Phys. Chem. Res.

• Yatagai Fumio

  Inst. Of Physical And Chemical

• Yatagai Fumio

  Ri Inst. Phys. Chem. Res.

• EGUCHI-KASAI Kiyomi

  Natl. Inst. Radiol. Sci.

• SATO Koki

  Natl. Inst. Radiol. Sci.

• EGUCHI-KASAI Kiyomi

  Division of Radiation Hazards

• ITSUKAICHI Hiromi

  Division of Radiation Hazards

• Kanai T

  National Institute Of Radiological Sciences

• Kanai Tatsuaki

  Department Of Accelerator And Medical Physics Research Center For Charged Particle Therapy National

• Fukutsu Kumiko

  Div. Radiotoxico. Protect

• Itsukaichi Hiromi

  Radiation Hazards Research Groupe Natl. Inst. Radiat Sci.

• Kojima Shuji

  Department Of Radiation Biosciences Faculty Of Pharmaceutical Sciences Tokyo University Of Science (

• Yatagai Fumio

  理化学研究所

• Mutoh Masahiro

  Division Of Physiology And Pathology

• Kanai Tatsuaki

  Div. Acce. Res. Natl. Inst. Radiol Sci.

• Kanai Tatsuaki

  Natl. Inst. Of Radiological Sciences

• Yatagai F

  Riken Institute

• Murakami Masahiro

  Radiation Hazards Research Group Nirs

関連論文

• An Approach to Estimate Radioadaptation from DSB Repair Efficiency
• LOH Analyses for Biological Effects of Space Radiation : Human Cell Culture in "Kibo" of International Space Station
• Two Major Factors Involved in the Reverse Dose-rate Effect for Somatic Mutation Induction are the Cell Cycle Position and LET Value
• Reversed dose-rate effect of high LET radiation in mutation induction
• Potentially Lethal Damage Repair by Total and Quiescent Tumor Cells Following Various DNA-damaging Treatments
• A Comparison of Biological Responses of Human Tumor Cells After Irradiation with Heavy Ions and Neutrons
• Response of human tumor cells in plateau phase and grown as spheroids to carbon beam irradiation.
• Development of a Radio-sensitive Mutation System for the Study of Dose Rate Effects of Space High LET Radiation
• Responses of total and quiescent cell populations in solid tumors to carbon ion beam irradiation (290 MeV/u) in vivo
• Evaluation of Late Radiation Damage of Normal Tissues in Mouse Hind Legs after Irradiation with Carbon Beams
• Dose response relations in acute cell death of pancreatic islets after irradiation of golden hamster with X-ray ,7OMeV proton and 290MeV carbon beams.
• Morphological Evaluation of Normal Tissue Damage after Neon Beam Irradiation in Mouse Hind Legs
• RBBs of 30MeV Fast Neutrons and 135MeV Carbon Beams for Clongenecities in Mouse Growing Tail Cartilage Cells.
• The effects of cell death and mutatlon induction lrradiated with acceterated carbon ion beams with spread out Bragg peak.
• Cosmetic Results and Complications after Breast Conserving Therapy for Early Breast Cancer
• Skin reaction after single doses of HIMAC Carbon-12 Spread- Out-Bragg-Peak
• Analysis of Mutations in the Human HPRT Gene Induced by accelerated heavy-ion irradiation
• LET dependence of biological effects in normal human cells irradiated wfth accelerated neon ions.
• Changes in the Pharmacokinetics of Gd-DTPA in Experimental Tumors after Charged Particle Radiation : Comparison with γ-Ray Radiation
• Mutation Induction in Cultured Human Cells after Low-dose and Low-dose-rate γ-ray Irradiation : Detection by LOH Analysis
• Induction of LOH events by Low-dose or Low-dose Rate Radiation Exposure
• Repair of Skin Damage During Fractionated Irradiation with Gamma Rays and Low-LET Carbon Ions
• Relative Biological Effectiveness of the 235 MeV Proton Beams at the National Cancer Center Hospital East
• Mutation Induction in the rspL gene on an E. coli-B. subtilis shuttle vector by Space Flight on MIR
• Tumor Induction in Mice Locally Irradiated with Carbon Ions : A Retrospective Analysis
• Qualitative and quantitative difference in mutation induction between carbon- and neon-ion beams in normal human cells
• Analysis of DNA damage checkpoint pathway in mammalian cells
• Cellular Responses after Heavy-ion Exposure
• Expression and localization of p53 and PARP in cultured mammalian cells exposed to accelerated Fe and Ar-ions
• Spectra of Linear Energy Transfer vs. Relative Biological Effectiveness for Accelerated Heavier Ions upon Clonogenic Survival of V79 Cells
• Judgement on "Hit or Non-hit" by Time-Lapse Observations of CHO Cells Exposed to Accelerated Iron-ions.
• Extension of In vitro Life-span of γ-irradiated Human Embryo Cells Accompanied by Chromosome Instability
• Analysis of Mutations in the Human HPRT Gene induced by High LET Heavy-ion Irradiation
• Time-Lapse Photographic Observation of CHO Cells Exposed to Accelerated Iron-Ions
• Mechanisms of Interphase-Death Induction for CHO Cells Exposed to Accelerated Heavy-Ions
• RBE and OER for Cell Killing upon V79 Cells by Heavy-Ion Beams at a Very High LET Region
• Analysis of Mutations in the Human HPRT Gene Induced by Heavy-ion Irradiation II
• Skin Shrinkage Caused by Neon-20 and Carbon-12
• LET Dependence of Interphase Cell-Death Induction by Accelerated Heavy-Ions
• Dependence of Interphase Cell-Death Induction on LET Values of Accelerated Heavy-Ions
• The effects of irradiated volume on early skin reaction after carbon ion beam irradiation.
• Biological effects of heavy-ion irradiation on DNA double-strand breaks repair deficient mutant cell line
• Response of Crypt Cell Survivals of Mouse Intestine after Fractionated Doses of Accelerated Carbon-Ion with Spread-Out Bragg Peak.
• Biological data for heavy-ion radiation therapy
• Analysis of Survival Curve Parameters caused by High-LET Accelerated Ion Beams, Cell Strains, and LETS
• Increase of mitotic indices in a human salivary gland tumor xenograft after irradiation with particle beams.
• Chromosome Aberrations Induced by Neon lon Beams Produced by RIKEN Ring Cyclotron in human lymphocytes of blood.
• Position Determination by Laser Marks of Biological Samples Placed on a Plastic Track Detector and Inactivation of B. subtilis Spores by a Single Heavy Ion
• Exploration of 'Over Kill Effect' of High-LET Ar-and Fe-ions by Evaluating the Fraction of Non-hit Cell and Interphase Death
• Sensitive Detection of LOH Events in a Human Cell Line after C-ion Beam Exposure
• Effect of a p53 codon 237 mutation on X-ray induced HPRT mutations
• Analysis of tk Mutation Induced by Low Dose Ionizing Radiation in Human Cells
• Contribution of mutant p53 protein to hyper recombination leading to enhancement of spontaneous mutation.
• Cellular Responses to Low Dose Heavy-ions in Human Cells
• p53 protein contributed to repair of double strand break
• p53 and p21 protein induction in TK6 and NS human lymphoblastoid cells after X-ray and heavy ion irradiations.
• Effect of Pre-irradiation by Small Dose Heavy-ions in Human Cells
• Judgement on "Hit or Non-Hit" for the Cells Exposed to High-LET Heavy-Ions (Fe,Ar)
• Analysis of Mutation Induced by Heavy-ion in Human HPRT Gene
• Mutation induction after low-dose carbon-ion beam irradiation of frozen human cultured cells
• Mutation induction in frozen human cultured cells caused by low-dose carbon ion irradiation
• Detection of Adaptive Response at Chromosome Level
• Radiosensitivity of Human Skin Cells in vitro to Accelerated Heavy Ions.
• A Single-Base Detection Methodology ; An Application of SSCP for Revertants of Mouse FM3A ts Mutant
• DNA PKcs-independent error-prone DNA end-joining pathway and its role in radiation-induced mutagenesis
• Mutation Spectrum in hMSH3-deficient ovarian tumor cell line HHUA/chr.2
• Mutation Induction by Heavy-ion irradiation of gpt Δ Transgenic Mouse
• A fate of DNA double strand breaks in mammalian cells
• A Basic Understanding of the Difficulty in SSCP Analysis
• Dosimetry for heavy-ion radiation fields of argon, iron and kripton beams.
• Effect of Heavy Ion Exposure on Cell Cycle Progression.
• Effect of Exposure of Heavy Ion Beams on G2 Arrest.
• Effect of exposure of carbon ion beams on cell cycle progression
• T cell lymphoma cells derived from SCID mouse are sensitive to X-ray Irradiation and beta-rays from ^C In DNA.
• Enhancement of cell killing by split exposure of hlgh LET heavy ion beams.
• LET Dependence for Somatic Mutation Cross Section of Drosophila Irradiated with Heavy Ion Beams
• LET Dependence for Induction of Drosophila Somatic Mutations Irradiated with Heavy Ion Beams.
• LET, cell cycle dependence for mutation induction and spectrum in HPRT locus
• Induction of Non-repairable DNA Strand Breaks by N-ion Beams
• Verification of ^C-290 MeV/u Tlieraputic Beams for HIMAC Clinical Trial using Mammalian cells
• Structural Analysis of Chromosome Damage Induced with X-ray or Heavy Ion Radiation by Atomic ForceMicroscope
• Bone marrow death is not always more sentitive than intestinal death in Mongolian gerbils ? II Radiosensitivity of bone marrow stem cells.
• Biological effects of active oxygen on the mouse cell rine defective in repair of DNA double-strand breaks
• LET-Dependence of Wing-hair and Eye-color Mosaic Spots Inductions at the Somatic Cells of Drosophila Larva Irradiated with 12C (290MeV/u) Ion Beams
• Expression of VEGF mRNA by irradiation with X-ray and heavy-ion beam
• Adenoid Cystic Carcinoma of the Tracheobronchial System : The Role of Postoperative Radiotherapy
• Effect of Heavy Ion Exposure on Cell Cycle Checkpoints.
• DNA strand breaks induced by carbon ions near the Bragg peak-Are DSBs induced more efficiently than SSBs?
• Energy-dependent RBE of Neutrons to Induce Micronuclei in Root-tip Cells of Allium cepa Onion Irradiated as Dry Dormant Seeds and Seedlings
• Relative Biological Effectiveness of Fission Neutrons for Producing Micronuclei in the Root-tip Cells of Onion Seedlings after Irradiation as Dry Seeds
• Effect of Heavy Ion Exposure on Cell Cycle Checkpoints.
• DNA strand breaks induced by heavy ions near the Bragg peak.
• Proteolytic cleavage of XRCC4 protein during apoptosis
• Low-Dose Irradiation Mediates Ca^ Signaling in Cultured Rat Hepatocytes
• Radioadaptation in Embryogenesis Is Related to p53 Gene Status
• Radioadaptation in Embryogenesis during Late Period of Organogenesis and Postnatal Retardation in the Prenatally Primed Mice
• Cell Kills and change of DNA Distribution of Human Tumor Cells by Fractionated Daily Irradiation in vitro.
• Cell cycle and LET dependence for 6-thioguanine-resistant mutation induced by heavy ion beam in mouse L5178Y cells
• Response of rat and human tracheal epithelial cells by air-liquid interface culture to ionizing radiation
• Acquired Radioresistance in Hematopoiesis in C57BL Mice

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