DISSEMINATED INTRAVASCULAR COAGULATION (DIC) IN RABBIT HAEMORRHAGIC DISEASE
スポンサーリンク
概要
- 論文の詳細を見る
Seven rabbits experimentally infected with rabbit haemorrhagic disease virus were examined haematologically and histologically. Haematologically, activated partial thromboplastin time and prothrombin time were markedly prolonged in the terminal phase of the disease, just prior to death (all the animals died between 27 and 40 hr after inoculation with rabbit haemorrhagic disease virus). There was an increase in the titre of fibrin degradation products and a decrease in antithrombin III activity during the same interval. Acute necrotic hepatitis and disseminated intravascular coagulation (DIC) in many organs, including the lung, kidney, spleen and heart were the characteristic histopathological changes. Thus, the haematological and histological changes suggested that DIC was induced by rabbit haemorrhagic disease virus infection. Severe liver necrosis was considered to be a factor causing DIC by inducing a hypercoagulable condition in the systemic blood circulation.
- 北海道大学の論文
- 1992-12-28
著者
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落合 謙爾
北海道大学大学院獣医学研究科比較病理学研究室
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Park Jae-hyuk
Toyohashi Univ. Tech.
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落合 謙爾
北海道大学大学院獣医学研究科比較病理学教室
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PARK Jong-Hwan
Department of Laboratory Animal Medicine
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PARK Jae-Hak
Department of Laboratory Animal Medicine
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Park Jae-hak
Dep. Of Lab. Animal Medicine Coll. Of Veterinary Medicine And Krf Zoonotic Disease Priority Res. Ins
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朴 載赫
豊橋技科大
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Park J‐h
Department Of Comparative Pathology Faculty Of Veterinary Medicine Hokkaido University
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Park Jae-hak
Department Of Comparative Pathology Faculty Of Veterinary Medicine Hokkaido University
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Park J‐h
Dep. Of Lab. Animal Medicine Coll. Of Veterinary Medicine And Krf Zoonotic Disease Priority Res. Ins
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Ochiai Kenji
Hokkaido Univ. Sapporo Jpn
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Ochiai Kenji
Department Of Applied Chemistry Graduate School Of Engineering Nagoya University:(present Address)ba
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Ueda Kaoru
Department Of Comparative Pathology Faculty Of Veterinary Medicine Hokkaido University
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Itakura Chitoshi
Department Of Comparative Pathology Faculty Of Veterinary Medicine Hokkaido University
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Ueda Kaoru
Department Of Applied Chemistry Nagoya Institute Of Technology
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