Microbiological Monitoring of Guinea Pigs Reared Conventionally at Two Breeding Facilities in Korea

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概要

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• In this study, microbiological monitoring of guinea pigs reared conventionally in two facilities was performed twice in 2004, with a three-month-interval between surveys. This study was based on the recommendations of the FELASA Working Group, with some modifications. In serological tests in the first survey, some animals from facility A showed positive results for Encephalitozoon cuniculi, Sendai virus, pneumonia virus of mice (PVM), and Reovirus-3 (Reo-3); facility B showed a positive result only for E. cuniculi. The results of the second survey were similar to the first, except for the presence of Sendai virus; all animals from the two facilities were Sendai virus-negative in the second experiment. No pathogenic bacteria were cultured in the organs of any of the animals in the first survey. However, in the second survey, Bordetella bronchiseptica was cultured from the lung tissue of two 10-week-old animals from facility A. Chlamydial infection was examined by the Macchiavello method, but no animal showed positive results. Tests using fecal flotation or the KOH wet mount method showed no infection of endoparasites, protozoa, ectoparasites, or dermatophytes in any animal in both surveys. However, in the histopathological examination, an infection of protozoa-like organisms was observed in the cecum of some animals from facility A. The present study revealed that microbiological contamination was present in guinea pigs reared conventionally in two facilities in Korea, suggesting that there is a need to improve environmental conditions in order to eradicate microbial contamination.

• 社団法人　日本実験動物学会の論文
• 2006-10-01

著者

• Park Jae-hyuk

  Toyohashi Univ. Tech.

• PARK Jong-Hwan

  Department of Laboratory Animal Medicine

• PARK Jae-Hak

  Department of Laboratory Animal Medicine

• Park Jae-hak

  Dep. Of Lab. Animal Medicine Coll. Of Veterinary Medicine And Krf Zoonotic Disease Priority Res. Ins

• 朴 載赫

  豊橋技科大

• Park J‐h

  Department Of Comparative Pathology Faculty Of Veterinary Medicine Hokkaido University

• Park Jae-hak

  Department Of Comparative Pathology Faculty Of Veterinary Medicine Hokkaido University

• Hwang Dae-youn

  Laboratory Animal Resources Team National Institute Of Toxicological Research

• SEOK Seung-Hyeok

  Department of Laboratory Animal Medicine, College of Veterinary Medicine and School of Agricultural

• BAEK Min-Won

  Department of Laboratory Animal Medicine, College of Veterinary Medicine and School of Agricultural

• LEE Hui-Young

  Department of Laboratory Animal Medicine, College of Veterinary Medicine and School of Agricultural

• KIM Dong-Jae

  Department of Laboratory Animal Medicine, College of Veterinary Medicine and School of Agricultural

• CHO Jung-Sik

  Laboratory Animal Resources Team, National Institute of Toxicological Research

• KIM Chuel-Kyu

  Laboratory Animal Resources Team, National Institute of Toxicological Research

• Seok Seung-Hyeok

  Institute for Experimental Animals, College of Medicine, Seoul National University

• Kim Dong-jae

  Dep. Of Lab. Animal Medicine Coll. Of Veterinary Medicine And Krf Zoonotic Disease Priority Res. Ins

• Park J‐h

  Dep. Of Lab. Animal Medicine Coll. Of Veterinary Medicine And Krf Zoonotic Disease Priority Res. Ins

• Kim Chuel-kyu

  Laboratory Animal Resources Team National Institute Of Toxicological Research

• Baek Min-won

  Dep. Of Lab. Animal Medicine Coll. Of Veterinary Medicine And Krf Zoonotic Disease Priority Res. Ins

• Cho Jung-sik

  Laboratory Animal Resources Team National Institute Of Toxicological Research

• Lee Hui-young

  Dep. Of Lab. Animal Medicine Coll. Of Veterinary Medicine And Krf Zoonotic Disease Priority Res. Ins

• Seok Seung-hyeok

  Institute For Experimental Animals College Of Medicine Seoul National University

• Lee Hui-young

  Department Of Laboratory Animal Medicine College Of Veterinary Medicine And Krf Zoonotic Disease Pri

• Baek Min-won

  Department Of Laboratory Animal Medicine College Of Veterinary Medicine And Krf Zoonotic Disease Pri

• Kim Dong-jae

  Department Of Laboratory Animal Medicine College Of Veterinary Medicine And Krf Zoonotic Disease Pri

• Park Jong-Hwan

  Department of Biochemistry, College of Medicine, Konyang University

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