MICRONUCLEUS TEST IN MICE FED ON AN IRRADIATED DIET
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概要
- 論文の詳細を見る
A mutagenicity study was carried out in mice fed on a γ-irradiated diet. As an indicator of mutagenic activity, we observed an incidence of micronuclei in erythrocytes. The average body weight of the mice fed on the diet irradiated to dose range of 400-1,000 kGy decreased, and the mice fed on the 800-1,000 kGy-irradiated diet died during the period from 8 to 14 days after the start of feeding. On the other hand, when the mutagenic activity of the irradiated diet was tested by observing occurrence of micronucleus in erythrocytes, no significant increase was recognized. These results indicated that the irradiated diet had no mutagenic activity, even though it possessed a toxic effect on the growth of mice.
- 北海道大学の論文
- 1989-06-20
著者
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SATO Fumiaki
Department of Surgical Neurology Jichi Medical School
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Sato F
Japan Racing Assoc. Utsunomia
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Sato Fumiaki
Faculty Of Veterinary Medicine Hokkaido Univ.
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Kuwabara Mikinori
Department Of Physics Faculty Of Science Hokkaido University
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Kuwabara Mikinori
Department Of Radiation Biology Faculty Of Veterinary Medicine Hokkaido University
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ENDOH Daiji
Department of Veterinary Radiology, School of Veterinary Medicine, Rakuno Gakuen University
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Sato F
Equine Research Institute
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HASHIMOTO Noriyoshi
Department of Radiation Biology, Faculty of Veterinary Medicine, Hokkaido University
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Endoh Daiji
Faculty Of Veterinary Medicine Hokkaido Univ.
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Sato F
Hokkaido Univ. Sapporo
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Hashimoto N
Institute For Experimental Animals School Of Medicine Kanazawa Univ.
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Sato Fumiaki
Department Of Computational Intelligence And Systems Science Tokyo Institute Of Technology
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Hashimoto Noriyoshi
Department Of Radiation Biology Faculty Of Veterinary Medicine Hokkaido University
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Sato Fumiaki
Department of Clinical Chemistry, School of Pharmacy and Pharmaceutical Sciences, Hoshi University
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ENDOH Daiji
Department of Basic Veterinary Radiology, School of Veterinary Medicine, Rakuno Gakuen University
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KUWABARA Mikinori
Department of Environmental Veterinary Science, Graduate School of Veterinary Medicine, Hokkaido University
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