Production of Age-Related DNA Strand Breakage in Brain Cells of Senescence-Accelerated Prone (SAMP1) Mouse
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概要
- 論文の詳細を見る
Amounts of DNA strand breaks were estimated by the proportion of cells without tails (PCWT) and the average lengths of tail momentum (ALTM) in comet images of tissue cells of senescence-accelerated prone (SAMP1) mouse and senescence-accelerated resistant (SAMR1) mouse. The PCWT and ALTM of brain cells from SAMR1 were unchanged from 4 to 15 months of age. In the case of SAMP1 brain cells, the PCWT decreased and the ALTM increased in an age-related manner from 8 to 15 months of age. In the cases of liver and kidney, the PCWT and the ALTM of both SAMP1 and SAMR1 cells showed constant values from 4 to 15 months of ages.
- 社団法人 日本実験動物学会の論文
- 2003-07-01
著者
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HAYASHI Masanobu
Department of Veterinary Radiology, School of Veterinary Medicine, Rakuno Gakuen University
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ENDOH Daiji
Department of Veterinary Radiology, School of Veterinary Medicine, Rakuno Gakuen University
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OKUI Toyo
Hokkaido Institute of Public Health
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Okui Toyo
酪農学園大学 獣医学部獣医放射線生物学
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Endoh Daiji
Faculty Of Veterinary Medicine Hokkaido Univ.
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Hayashi Masanobu
Department Of Experimental Radiobiology Faculty Of Veterinary Medicine Hokkaido University
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NISHIDA Koga
Department of Veterinary Radiology, School of Veterinary Medicine, Rakuno Gakuen University
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Nishida Koga
Department Of Veterinary Radiology School Of Veterinary Medicine Rakuno Gakuen University
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Hayashi Masanobu
Department Of Veterinary Radiology School Of Vterinary Medicine Rakuno Gakuen University
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ENDOH Daiji
Department of Basic Veterinary Radiology, School of Veterinary Medicine, Rakuno Gakuen University
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HAYASHI Masanobu
Department of Basic Veterinary Radiology, School of Veterinary Medicine, Rakuno Gakuen University
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