S期でX線照射されたLECラット細胞のG2/M期における異常な蓄積
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概要
- 論文の詳細を見る
The effect of X-irradiation on the progression of the cell cycle in cell lines from LEC and WKAH rats was investigated by a flow cytometer. When the cells were exposed to 5 Gy of X-rays at S phase, the proportion of S-phase cells in both cell populations decreased with incubation time and that of G2/M-phase cells was approximately 80% at 6 hr post-irradiation. At 12 hr post-irradiation, approximately 45% of the WKAH rat cells appeared in the G1 phase. However, 80-90% of LEC rat cells remained in the G2/M phase and less than 5% in the G1 phase during 6-12 hr post-irradiation. Thus, the LEC rat cells irradiated at S phase remained in the G2/M phase for at least 6 hr longer than did the WKAH rat cells.
- 社団法人日本獣医学会の論文
- 1999-08-25
著者
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HAYASHI Masanobu
Department of Veterinary Radiology, School of Veterinary Medicine, Rakuno Gakuen University
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OKUI Toyo
Hokkaido Institute of Public Health
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Okui T
Hokkaido Inst. Public Health Sapporo Jpn
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Arai Soichiro
Department Of Veterinary Radiology Faculty Of Veterinary Medicine Rakuno Gakuen University
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Arai Soichiro
Department Of Experimental Radiobiology Faculty Of Veterinary Medicine Hokkaido University
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Hayashi Masanobu
Department Of Veterinary Radiology Faculty Of Veterinary Medicine Rakuno Gakuen University
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Hayashi Masanobu
Department Of Experimental Radiobiology Faculty Of Veterinary Medicine Hokkaido University
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KUZUMI Toshio
Department of Veterinary Radiology, Faculty of Veterinary Medicine, Rakuno Gakuen University
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Kuzumi Toshio
Department Of Veterinary Radiology Faculty Of Veterinary Medicine Rakuno Gakuen University
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林 正信
Department of Veterinary Radiology, Faculty of Veterinary Medicine, Rakuno Gakuen University
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葛見 敏男
Department of Veterinary Radiology, Faculty of Veterinary Medicine, Rakuno Gakuen University
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荒井 惣一郎
Department of Veterinary Radiology, Faculty of Veterinary Medicine, Rakuno Gakuen University
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林 正信
Department of Basic Veterinary Radiology, School of Veterinary Medicine, Rakuno Gakuen University
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