Resistance to UV-Irradiation of DNA Synthesis in Fibroblast Cell Lines Derived from LEC Strain Rats.
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概要
- 論文の詳細を見る
After UV-irradiation, no difference in the survival curves was observed among cell lines derived from LEC strain (LEC) rats and WKAH strain (WKAH) rats. The dose-response curves for inhibition of DNA synthesis in WKAH-derived cells showed a sharp decline at lower doses and a mild decline at higher doses of UV-rays. In contrast, the dose-response curves in LEC-derived cell lines had no sharp component, and were almost identical to the mild component of the curves in WKAH-derived cells. These results show that DNA synthesis in the cell lines of LEC rats was more resistant to UV-irradiation than that of WKAH rats.
- 公益社団法人 日本獣医学会の論文
著者
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OKUI Toyo
Hokkaido Institute of Public Health
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Arai Soichiro
Department Of Experimental Radiobiology Faculty Of Veterinary Medicine Hokkaido University
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HAYASHI Masanobu
Department of Basic Veterinary Radiology, School of Veterinary Medicine, Rakuno Gakuen University
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HAYASHI Masanobu
Department of Veterinary Radiology, Faculty of Veterinary Medicine, Rakuno Gakuen University
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UEHARA Kazuhisa
Department of Veterinary Radiology, Faculty of Veterinary Medicine, Rakuno Gakuen University
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