<原著>精神的ストレス時の内因性エピネフリン分泌と心血行動態

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We evaluated the quantitative correlations between cardiovascular and plasma catecholamine responses to 2 minutes mental arithmetic test in 21 young healthy males, aging 18-29 years. Serial estimation of heart rate (HR), systolic and diastolic blood pressure (SBP, DBP), and plasma epinephrine and norepinephrine (Ep, NEp) was perfomed before, during, and after the test. The results were as follows; (1) HR. SBP, DBP, and Ep were significantly increased during the test, but NEp showed variable changes and unaltered as a whole, (2) Resting plasma catecholamine levels showed no correlations with resting cardiovascular parameters, (3) Increase in Ep during the test showed significant correlations with increase in HR, SBP, but not with DBP. (4) Changes in NEp during the test showed no correlations with changes in HR. SBP and DBP. We concluded that mental stress elicts significant cardiovascular responses which correlated with endogenous Ep secretion in young healthy males. (Journal of Health Science, Kyushu University. 10: 109-113, 1988)
1988-02-20