Induction of Multiple Cytokine Secretion from RAW264.7 Cells by Alginate Oligosaccharides
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概要
- 論文の詳細を見る
We investigated the cytokine-inducing activities of guluronate (G3–G6) and mannuronate (M3–M6) oligomers on RAW264.7 cells with the Bio-Plex assay system. Relatively high levels of tumor necrosis factor-α (TNF-α), granulocyte colony-stimulating factor (G-CSF), monocyte chemoattractant protein-1 (MCP-1), regulated upon activation normal T cell expressed and secreted (RANTES), granulocyte macrophage (GM)-CSF, and eotaxin were induced by alginate oligomers to different extents depending on the oligomer structures, and low but significant levels of interleukin (IL)-1α, IL-1β, IL-6, IL-9, and IL-13 were also induced. Throughout all cytokines tested, M-oligomers tended to be more potent than G-oligomers in terms of cytokine induction, and this tendency was evident in differences between G3 and M3.
- 社団法人 日本農芸化学会の論文
- 2007-01-23
著者
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Oda Tatsuya
Division Of Biochemistry Faculty Of Fisheries Nagasaki University
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Oda Tatsuya
Div. Of Biochemistry Fac. Of Fisheries Nagasaki Univ.
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Oda T
Division Of Biochemistry Faculty Of Fisheries Nagasaki University
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YAMAGUCHI Kenichi
Division of Biochemistry, Faculty of Fisheries, Nagasaki University
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YAMAMOTO Yoshiko
Division of Biochemistry, Faculty of Fisheries, Nagasaki University
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KURACHI Maki
Division of Biochemistry, Faculty of Fisheries, Nagasaki University
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Yamaguchi Kenichi
Division Of Biochemistry Faculty Of Fisheries Nagasaki University
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Kurachi Maki
長崎大学 水産学部
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Kurachi Maki
Division Of Biochemistry Faculty Of Fisheries Nagasaki University
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Tatsuya Oda
Division Of Biochemistry Faculty Of Fisheries Nagasaki University
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Oda T
Nagasaki Univ. Nagasaki Jpn
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Oda T
New Industry Creation Hatchery Center Tohoku University
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Okamoto Tarou
Division Of Biochemistry Faculty Of Fisheries Nagasaki University
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Yamamoto Yoshiko
Division Of Biochemistry Faculty Of Fisheries Nagasaki University
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Yamasaki Yasuhiro
Division Of Biochemistry Faculty Of Fisheries Nagasaki University
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Oda T
Faculty Of Fisheries Nagasaki University
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Yamaguchi Kenichi
New Industry Creation Hatchery Center Tohoku University
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YAMAGUCHI Kenichi
Division of Allergy and Rheumatology, St. Luke's International Hospital
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