Induction of Multiple Cytokine Secretion from RAW264.7 Cells by Alginate Oligosaccharides
スポンサーリンク
概要
- 論文の詳細を見る
We investigated the cytokine-inducing activities of guluronate (G3–G6) and mannuronate (M3–M6) oligomers on RAW264.7 cells with the Bio-Plex assay system. Relatively high levels of tumor necrosis factor-α (TNF-α), granulocyte colony-stimulating factor (G-CSF), monocyte chemoattractant protein-1 (MCP-1), regulated upon activation normal T cell expressed and secreted (RANTES), granulocyte macrophage (GM)-CSF, and eotaxin were induced by alginate oligomers to different extents depending on the oligomer structures, and low but significant levels of interleukin (IL)-1α, IL-1β, IL-6, IL-9, and IL-13 were also induced. Throughout all cytokines tested, M-oligomers tended to be more potent than G-oligomers in terms of cytokine induction, and this tendency was evident in differences between G3 and M3.
著者
-
Oda Tatsuya
Division Of Biochemistry Faculty Of Fisheries Nagasaki University
-
YAMAGUCHI Kenichi
Division of Biochemistry, Faculty of Fisheries, Nagasaki University
-
YAMAMOTO Yoshiko
Division of Biochemistry, Faculty of Fisheries, Nagasaki University
-
KURACHI Maki
Division of Biochemistry, Faculty of Fisheries, Nagasaki University
-
Yamaguchi Kenichi
Division Of Biochemistry Faculty Of Fisheries Nagasaki University
-
Yamamoto Yoshiko
Division Of Biochemistry Faculty Of Fisheries Nagasaki University
関連論文
- Mitogenic Activity of CEL-I, an N-Acetylgalactosamine (GalNAc)-Specific C-Type Lectin, Isolated from the Marine Invertebrate Cucumaria echinata (Holothuroidea)
- CEL-I, an N-acetylgalactosamine (GalNAc)-specific C-type lectin, induces nitric oxide production in RAW264.7 mouse macrophage cell line.
- Effects of sulfated fucan, ascophyllan, from the brown Alga Ascophyllum nodosum on various cell lines: a comparative study on ascophyllan and fucoidan.
- Induction of Multiple Cytokine Secretion from RAW264.7 Cells by Alginate Oligosaccharides
- CEL-I, an Invertebrate N-Acetylgalactosamine-specific C-Type Lectin, Induces TNF-α and G-CSF Production by Mouse Macrophage Cell Line RAW264.7 Cells
- Apoptosis-Mediated Cytotoxicity of Prodigiosin-Like Red Pigment Produced by γ-Proteobacterium and Its Multiple Bioactivities
- Evaluation of the anti-Trichophyton activity of a prodigiosin analogue produced by γ-proteobacterium, using stratum corneum epidermis of the Yucatan micropig
- Characterization of Bacterium Isolated from the Sediment at Coastal Area of Omura Bay in Japan and Several Biological Activities of Pigment Produced by This Isolate
- Cytotoxicity of a GalNAc-Specific C-Type Lectin CEL-I toward Various Cell Lines
- Butyric Acid Sensitizes Vero Cells to Ricin-Induced Apoptosis via Accelerated Activation of Multiple Signal Transduction Pathways
- Evaluation of the potential biological toxicities of aqueous extracts from red tide phytoplankton cultures in in vitro and in vivo systems
- Detection of Nitric Oxide(NO) in Marine Phytoplankters(MICROBIAL PHYSIOLOGY AND BIOTECHNOLOGY)
- Selective Toxic Effects of Polyunsaturated Fatty Acids Derived from Ulva fasciata on Red Tide Phyotoplankter Species
- Production of Superoxide Anion and Hydrogen Peroxide by the Red Tide Dinoflagellate Karenia mikimotoi (MICROBIAL PHYSIOLOGY AND BIOTECHNOLOGY)
- Comparison of Hemolytic Activities Among Strains of Heterocapsa circularisquama Isolated in Various Localities in Japan(Biochemistry & Molecular Biology)
- Specific Toxic Effect of Dinoflagellate Heterocapsa circularisquama on the Rotifer Brachionus plicatilis
- Concanavalin A-Induced Discharge of Glycocalyx of Raphidophycean Flagellates, Chattonella marina and Heterosigma akashiwo
- Galacturonic-acid-induced Increase of Superoxide Production in Red Tide Phytoplankton Chattonella marina and Heterosigma akashiwo
- Isolation and Characterization of a Mutant Strain of Chattonella marina with Decreased Production of Superoxide Anion
- A Prodigiosin Analogue Inactivates NADPH Oxidase in Macrophage Cells by Inhibiting Assembly of p47phox and Rac
- Root Growth-promoting Activity of Unsaturated Oligomeric Uronates from Alginate on Carrot and Rice Plants(Biochemistry & Molecular Biology)
- A Study of Tryptophan Fluorescence Quenching of Bifunctional Alginate Lyase from a Marine Bacterium Pseudoalteromonas sp. Strain No. 272 by Acrylamide(Biochemistry & Molecular Biology)
- Enzymatically Depolymerized Alginate Oligomers That Cause Cytotoxic Cytokine Production in Human Mononuclear Cells(Biochemistry & Molecular Biology)
- Resistance Against Ricin-Induced Apoptosis in a Brefeldin A -Resistant Mutant Cell Line (BER-40) of Vero Cells
- Comparison of the Apoptosis-inducing Abilities of Various Protein Synthesis Inhibitors in U937 Cells(Biochemistry & Molecular Biology)
- Calcium-sensitive extracellular poly (α-L-guluronate) lyase from a marine bacterium Pseudomonas sp. strain F6 : Purification and some properties
- Purification and Characterization of Bifunctional Alginate Lyase from Alteromonas sp. Strain No. 272 and Its Action on Saturated Oligomeric Substrates
- Fish Mucus Stimurates the Generation of Superoxide Anion by Chattonella marina and Heterosigma akashiwo
- Hemagglutinating Activity of Extracellular Alkaline Metalloendopeptidases from Vibrio sp. NUF-BPP1
- Generation of Reactive Oxygen Species by Raphidophycean Phytoplankton
- Catalase- and Superoxide Dismutase-induced Morphological Changes and Growth Inhibition in the Red Tide Phytoplankton Chattonella marina
- Hydrogen Peroxide Production by the Red-tide Flagellate Chattonella marina
- Growth-Promoting Effect of Alginate Oligosaccharides on a Unicellular Marine Microalga, Nannochloropsis oculata
- Cloning and Sequence Analyais of a Gene (bly PG) Encoding Poly(α-L-guluronate)lyase from Corynebacterium sp.Strain ALY-1
- Detection and Pharmacokinetics of Alginate Oligosaccharides in Mouse Plasma and Urine after Oral Administration by a Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS) Method
- Enhancement of Diphtheria Toxin-induced Apoptosis in Vero Cells by Combination Treatment with Brefeldin A and Okadaic Acid
- Detoxifying ability of marine bacterium Flavobacterium sp.against a toxic contaminant in the reagent sodium chloride to Nannochloropsis oculata
- Inhibitory Effect of Dideoxyforskolin on Cell Death Induced by Ricin, Modeccin, Diphtheria Toxin, and Pseudomonas Toxin in MDCk Cells
- The Possibility of Reactive Oxygen Species (ROS)-Independent Toxic Effects of Cochlodinium polykrikoides on Damselfish (Chromis caerulea)
- Characterization of Recombinant CEL-I, a GalNAc-Specific C-Type Lectin, Expressed in Escherichia coli Using an Artificial Synthetic Gene
- CEL-I, an N-acetylgalactosamine (GalNAc)-specific C-type lectin, induces nitric oxide production in RAW264.7 mouse macrophage cell line.
- Depletion of Intracellular NAD^+ and ATP Levels during Ricin-Induced Apoptosis through the Specific Ribosomal Inactivation Results in the Cytolysis of U937 Cells
- Isolated Ricin B-Chain-mediated Apoptosis in U937 Cells
- Effects of Glutathione-related Compounds on Increased Caspase-3 and Caspase-6-like Activities in Ricin-treated U937 Cells
- Specific Efflux of Glutathione from the Basolateral Membrane Domain in Polarized MDCK Cells during Ricin-Induced Apoptosis
- Involvement of N-Acetylcysteine-sensitive Pathways in Ricin-induced Apoptotic Cell Death in U937 Cells
- Involvement of Both Caspase-Like Proteases and Serine Proteases in Apoptotic Cell Death Induced by Ricin, Modeccin, Diphtheria Toxin, and Pseudomonas Toxin
- Diisopropylfluorophosphate (DFP) Inhibits Ricin-induced Apoptosis of MDCK Cells
- Temperature- and pH-Dependent Cytotoxic Effect of the Hemolytic Lectin CEL-III from the Marine Invertebrate Cucumaria echinata on Various Cell Lines
- Some Molecular and Inhibitory Specifications of a Dipeptidyl Carboxypeptidase from the Polychaete Neanthes virens Resembling Angiotensin I Converting Enzyme
- Induction of TNF-α Production from Human Peripheral Blood Monocytes with β-1,3-Glucan Oligomer Prepared from Laminarin with β-1,3-Glucanase from Bacillus clausii NM-1
- Cell Lysis Induced by Ricin D and Ricin E in Various Cell Lines
- Spectroscopic Studies on Denaturants and Guluronate Lyase from a Marine Bacterium
- An Improved Plate Method, in the Presence of Calcium Chloride or Sulfuric Acid, for Simultaneous Detection of Alginate Lyases(Biological Chemistry)
- Mitogenic Properties of Pokeweed Lectin-D Isoforms on Human Peripheral Blood Lymphocytes : Non-mitogen PL-D1 and Mitogen PL-D2
- Induction of Multiple Cytokine Secretion from RAW264.7 Cells by Alginate Oligosaccharides
- The Possibility of Reactive Oxygen Species (ROS)-Independent Toxic Effects of Cochlodinium polykrikoides on Damselfish (Chromis caerulea)
- Mitogenic Activity of CEL-I, an N-Acetylgalactosamine (GalNAc)-Specific C-Type Lectin, Isolated from the Marine Invertebrate Cucumaria echinata (Holothuroidea)
- Biological Activities of Fucose-Containing Polysaccharide Ascophyllan Isolated from the Brown Alga Ascophyllum nodosum
- Growth-Promoting Effect of Alginate Oligosaccharides on a Unicellular Marine Microalga, Nannochloropsis oculata
- Detection and Pharmacokinetics of Alginate Oligosaccharides in Mouse Plasma and Urine after Oral Administration by a Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS) Method
- Selective Toxic Effects of Polyunsaturated Fatty Acids Derived from Ulva fasciata on Red Tide Phyotoplankter Species
- Effect of the Hemolytic Lectin CEL-III from Holothuroidea Cucumaraia echinata on the ANS Fluorescence Responses in Sensitive MDCK and Resistant CHO Cells
- Cross-Talk between the Pathways Leading to the Induction of Apoptosis and the Secretion of Tumor Necrosis Factor-α in Ricin-Treated RAW 264.7 Cells
- Effects of alginate oligosaccharide mixtures on the growth and fatty acid composition of the green alga Chlamydomonas reinhardtii.
- Comparative Study on the Toxic Effects of Red Tide Flagellates Heterocapsa circularisquama and Chattonella marina on the Short-Necked Clam (Ruditapes philippinarum)
- Immunostimulatory Activities of the Sulfated Polysaccharide Ascophyllan from Ascophyllum nodosum in in Vivo and in Vitro Systems
- Transitional Reactive Oxygen Species (ROS) Production in Fertilized Egg Embryos of Devil Stinger (Inimicus japonicus), a Marine Fish Species