Effects of Sarin on the Nervous System of Subway Workers Seven Years after the Tokyo Subway Sarin Attack
スポンサーリンク
概要
- 論文の詳細を見る
This study was designed to assess the after effects of sarin exposure on the nervous system in victims of the Tokyo Subway Sarin Attack, which occurred on 20 March, 1995. We performed a similar study 3 yr after the disaster. This time, we newly enrolled 36 staff of the Teito Rapid Transit Authority (Tokyo Eidan subway) to assess the 7 yr after effects on the nervous system, and merged previous data including unpublished data to enhance statistical power. New subjects consisted of 23 male exposed subjects and 13 referent subjects matched for age and working types. Neurobehavioral tests for psychomotor function and memory, stabilometry, and Benton visual retention test were performed. As reported previously, the exposed group performed significantly less well in the psychomotor function test (tapping) than the referent group (117.8±1.2 vs. 105.6±1.2 msec). Using merged data, this phenomenon was also observed in a dose-dependent manner and the exposed group performed significantly less well in the backward digit span test (4.47±1.17 vs. 5.11±1.65 digits). These results indicate that chronic decline of psychomotor function and memory function still exist 7 yr after the sarin exposure.
- 社団法人日本産業衛生学会の論文
著者
-
NISHIWAKI Yuji
Department of Preventive Medicine and Public Health, Keio University School of Medicine
-
KIKUCHI Yuriko
Department of Preventive Medicine and Public Health, Keio University School of Medicine
-
MIYAKI Koichi
Department of Preventive Medicine and Public Health, School of Medicine, Keio University
-
KUMAGAI Nami
Department of Preventive Medicine and Public Health, School of Medicine, Keio University
-
MATSUMOTO Yukio
Department of Preventive Medicine and Public Health, School of Medicine, Keio University
-
Omae Kazuyuki
Department Of Preventive Medicine And Public Health School Of Medicine Keio University
-
Omae Kazuyuki
慶応義塾大学 医学部衛生学公衆衛生学
-
Omae Kazuyuki
慶應義塾大学医学部衛生学公衆衛生学教室
-
Omae Kazuyuki
Department Of Preventive Medicine And Public Health Keio University School Of Medicine
-
Omae Kazuyuki
東京医科歯科大学難治疾患研究所 分子疫学
-
YOSHIMURA Kimio
Cancer Information and Epidemiology Division, National Cancer Center Research Institute
-
MAEKAWA Kazuhiko
Kanto Central Hospital
-
Asukai Nozomu
Tokyo Metropolitan Institute Of Psychiatry
-
OGAWA Yasutaka
National Institute of Industrial Health
-
ETOH Norihito
Department of Preventive Medicine and Public Health, School of Medicine, Keio University
-
Asukai Nozomu
Tokyo Institute Of Psychiatry
-
Oda Kenichi
Department Of Preventive Medicine & Public Health School Of Medicine Keio University
-
Kikuchi Y
Department Of Preventive Medicine And Public Health Keio University School Of Medicine
-
Miyaki Koichi
Bureaus Of Social Welfare And Public Health Tokyo Metropolitan Government
-
Miyaki Koichi
Department Of Preventive Medicine And Public Health School Of Medicine Keio University
-
Kikuchi Yuriko
Department Of Preventive Medicine And Public Health School Of Medicine Keio University
-
Kikuchi Yuriko
Department Of Nutrition Science Tokyo University Of Agriculture
-
Nishiwaki Yuji
Department Of Preventive Medicine And Public Health School Of Medicine Keio University
-
Nishiwaki Yuji
Department Of Preventive Medicine And Public Health Keio University School Of Medicine
-
Nishiwaki Yuji
Department Of Preventive Medicine And Public Health Keio University
-
Kumagai Nami
Department Of Preventive Medicine And Public Health School Of Medicine Keio University
-
Yoshimura Kimio
Cancer Information And Epidemiology Division National Cancer Center Research Institute
-
Yoshimura Kimio
Cancer Information And Epidemiology Division Research Institute National Cancer Center
-
Etoh Norihito
Graduate School Of Science And Technology Keio University
-
Matsumoto Yukio
Department Of Geology Faculty Of Liberal Arts Nagasaki University
-
Mizutari Kunio
Dep. Of Otorhinolaryngology Head And Neck Surgery School Of Medicine Keio Univ.
-
Matsumoto Yukio
Department Of Preventive Medicine And Public Health School Of Medicine Keio University
-
Miyaki Koichi
Department Of Clinical Research And Informatics National Center For Global Health And Medicine
-
Matsumoto Yukio
Department Of Anesthesiology Fukushima Medical University School Of Medicine
-
Omae K
慶應義塾大学医学部衛生学公衆衛生学教室
-
NISHIWAKI Yuji
Department of Environmental and Occupational Health, Faculty of Medicine, Toho University
-
Nishiwaki Yuji
Department of Preventive Medicine and Public Health, School of Medicine, Keio University
-
Nishiwaki Yuji
Department of Environmental and Occupational Health, School of Medicine, Toho University
関連論文
- Lifestyle Factors and Visible Skin Aging in a Population of Japanese Elders
- The taste of salt measured by a simple test and blood pressure in Japanese women and men
- Effects of SO_2 on Respiratory System of Adult Miyakejima Resident 2 Years after Returning to the Island
- Association of Thoracic Kyphosis with Subjective Poor Health, Functional Activity and Blood Pressure in the Community-Dwelling Elderly
- Biological Monitoring of Indium by Means of Graphite Furnace Atomic Absorption Spectrophotometry in Workers Exposed to Particles of Indium Compounds
- Lack of Relationship between Occupational Exposure to Carbon Disulfide and Endocrine Dysfunction : A Six-year Cohort Study of the Japanese Rayon Workers
- Uptake of Cadmium in Meals from the Digestive Tract of Young Non-smoking Japanese Female Volunteers
- Urinary Excretion of TTCA after Intake of brassica Vegetables
- Cross-Sectional Study of Health Effects of Methyl Methacrylate Monomer among Dental Laboratory Technicians
- Four-Week Inhalation Toxicity Study of 2, 2-Dichloro-1, 1, 1-trifluoroethane(HCFC-123) in Guinea Pigs
- Acute and Recurrent Hepatitis Induced by 2, 2-Dichloro-1, 1, 1-trifluoroethane (HCFC-123)
- Relationship Between the Blood Coagulation-Fibrinolysis System and the Subclinical Indicators of Arteriosclerosis in a Healthy Male Population
- Stabilometry in Epidemiologieal Use : Measurement Bias by Different Instructions
- Environmental and Biological Monitoring of 2, 2-Dichloro-1, 1, 1-trifluoroethane (HCFC-123)
- Exposure to 2, 2-Dichloro-1, 1, 1-trifluoroethane (HCFC-123) and Acute Liver Dysfunction: A Causal Inference
- Toxicity of Silicon Compounds in Semiconductor Industries
- Toxicity of Intratracheally-administered Indium Phosphide(InP)in Rats.
- Acute Liver Dysfunction among Workers Exposed to 2, 2-Dichloro-1, 1, 1-trifluoroethane (HCFC-123) : A Case Report
- Respiratory Diseases and Working in a Copper or an Aluminum Product Plant:A Case Control Study by Using Medical Records
- A Simple Method for Carbon Disulfide Monitoring Using a Diffusive Sampler, Thermal Desorption and a Stain Tube
- Genotoxicity Studies of Heavy Metals : Lead, Bismuth, Indium, Silver and Antimony
- Oral Toxicity of Indium in Rats : Single and 28-Day Repeated Administration Studies
- Oral Toxicity of Bismuth in Rat : Single and 28-Day Repeated Administration Studies
- A 13-Week Toxicity Study of Bismuth in Rats by Intratracheal Intermittent Administration
- Influenza Antibody Titers after Vaccination of Chronic Renal Failure Patients : before and during Hemodialysis, or on Continuous Ambulatory Peritoneal Dialysis
- Three Cases of Acute Massive Hydrothorax Complicating Continuous Ambulatory Peritoneal Dialysis (CAPD)
- Continuous Ambulatory Peritoneal Dialysis in a Diabetic Patient with Renal Insufficiency and Ventricular Aneurysm
- One-leg standing test for elderly populations
- Health Effects of Chronic Exposure to Polychlorinated Dibenzo-P-Dioxins (PCDD), Dibenzofurans (PCDF) and Coplanar PCB (Co-PCB) of Municipal Waste Incinerator Workers
- Effects of Intratracheally Administered Indium Phosphide on Male Fischer 344 Rats
- Prognostic Factor Analysis of Early Death in Stage II Breast Cancer
- Pathological Changes in the Gastrointestinal Tract of a Heavily Radiation-exposed Worker at the Tokai-mura Criticality Accident
- Surgical site infection surveillance after open gastrectomy and risk factors for surgical site infection
- Applicability of the Stages of Change Model for Analyzing Fruit and Vegetable Intake in Relation to Urinary Potassium Excretion : Baseline Results from the High-Risk and Population Strategy for Occupational Health Promotion (HIPOP-OHP) Study
- Stages of Change for Salt Intake and Urinary Salt Excretion : Baseline Results from the High-Risk and Population Strategy for Occupational Health Promotion (HIPOP-OHP) Study
- Prevalence of ulcerative colitis and Crohn's disease in Japan
- Association of Thoracic Kyphosis with Subjective Poor Health, Functional Activity and Blood Pressure in the Community-Dwelling Elderly
- High throughput multiple combination extraction from large scale polymorphism data by exact tree method
- Serum cholesterol, uric acid and cholinesterase in victims of the Tokyo subway sarin poisoning : A relation with post-traumatic stress disorder
- Allele frequencies of single nucleotide polymorphisms (SNPs) in 40 candidate genes for gene-environment studies on cancer : data from population-based Japanese random samples
- Genetic Structure of the Five-factor Model of Personality in a Japanese Twin Population
- Personality and Dietary Habits
- Health Consciousness of Young People in Relation to their Personality
- Assessment of tailor-made prevention of atherosclerosis with folic acid supplementation : randomized, double-blind, placebo-controlled trials in each MTHFR C677T genotype
- Short-term Changes in Cadmium in Feces, Blood and Urine after Dietary Cadmium Intake in Young Japanese Females
- Cadmium Concentration in Current Japanese Foods and Beverages
- N,N-Dimethylformamide (DMF) Vapor Absorption through the Skin in Workers
- A Cross-Sectional Observation of the Effects of Hydrazine Hydrate on Workers' Health
- In Vitro Solubility and In Vivo Toxicity of Indium Phosphide
- Paradoxical increases in serum levels of highly chlorinated PCBs in aged women in clear contrast to robust decreases in dietary intakes from 1980 to 2003 in Japan
- Secular Trends and Geographical Variations in the Dietary Intake of Polybrominated biphenyl Ethers (PBDEs) Using Archived Samples from the Early 1980s and Mid 1990s in Japan
- Assessment of Conventional and New Prediction Algorithm for Multifactorial Disease Diagnosis
- Novel Statistical Classification Model of Type 2 Diabetes Mellitus Patients for Tailormade Prevention Using Data Mining Algorithm
- Causal Relationship between Indium Compound Inhalation and Effects on the Lungs
- Urinary Excretion of an Oxidative Stress Marker, 8-hydroxyguanine (8-OH-Gua), among Nickel-cadmium Battery Workers
- Effects of Sarin on the Nervous System of Subway Workers Seven Years after the Tokyo Subway Sarin Attack
- Expression of Platelet-derived Endothelial Cell Growth Factor/Thymidine Phosphorylase in Human Bladder Cancer
- Two New Criteria of the Metabolic Syndrome : Prevalence and the Association with Brachial-Ankle Pulse Wave Velocity in Japanese Male Workers
- PEGMATITE FROM NESOYA ISLAND, LUTZOW-HOLM BAY, EAST ANTARCTICA : WITH SPECIAL REFERENCE TO GARNET-QUARTZ SYMPLEKTITE
- Influence of Chronic UV Exposure and Lifestyle on Facial Skin Photo-Aging : Results from a Pilot Study
- A Classification for Some Small Chondrites in the Yamato-74 and -75 Meteorites
- Mineralogical Examination of the Yamato-75 Achondrites and Their Layered Crust Model
- A Classification of the Yamato-75 Chondrites Based on Chemical Compositions of Olivines and Pyroxenes
- Toxicity of Fire Decomposition Products of New Fire Extinguishing Agent, 1, 1, 1, 2, 3, 3, 3-Heptafluoropropane
- Acute and Subacute Inhalation Toxicity of Highly Purified Phosphine (PH_3) in Male ICR Mice
- Interaction of Angiotensin I-Converting Enzyme Insertion-Deletion Polymorphism and Daily Salt Intake Influences Hypertension in Japanese Men
- Schizophrenia : Is it time to replace the term?
- Longitudinal magnetic resonance imaging study on whiplash injury patients : minimum 10-year follow-up
- Personality Assessment Based on the Five-factor Model of Personality Structure in Patients with Primary Open-Angle Glaucoma
- Anterior Cervical Decompression and Fusion Accelerates Adjacent Segment Degeneration : Comparison With Asymptomatic Volunteers in a Ten-Year Magnetic Resonance Imaging Follow-up Study
- Aging of the Cervical Spine in Healthy Volunteers : A 10-Year Longitudinal Magnetic Resonance Imaging Study
- Absence of Germline CHK2 Mutations in Familial Gastric Cancer
- The Stability of the Oxidative Stress Marker, Urinary 8-hydroxy-2'-deoxyguanosine (8-OHdG), when Stored at Room Temperature
- Analysis of Urinary Metabolites of Polycyclic Aromatic Hydrocarbons in Incineration Workers
- Gernet-sillimanite gneisses from the Lutzow-Holm Bay region East Antarctica
- Mg-Al skarn of the Skallevikhalsen on the east coast of Lutzow-Holm Bay, East Antarctica
- The Evaluation of Materials to Provide Health-Related Information as a Population Strategy in the Worksite : The High-Risk and Population Strategy for Occupational Health Promotion (HIPOP-OHP) Study(Special Issue)
- Epidemiology of suicidal ideation and help-seeking behaviors among the elderly in Japan
- Perioperative respiratory complications caused by cystic lung malformation in Proteus syndrome
- Prevalence and Factors Associated with Tinnitus : A Community-Based Study of Japanese Elders
- Changes of Intestinal Flora of Young Japanese Females Resulting from Two-Week Common Diet and Living in the Same Dormitory
- Outline of disease gene hunting approaches in the Millennium Genome Project of Japan
- Prospective Ten-Year Follow-up Study Comparing Patients With Whiplash-Associated Disorders and Asymptomatic Subjects Using Magnetic Resonance Imaging
- Age-Related Changes of Thoracic and Cervical Intervertebral Discs in Asymptomatic Subjects
- The Psychological Characteristcs of Tobacco Dependence in a Rural Area of Japan
- On homogeneity of the Yamato-75110 chondrite
- A Brachina-like inclusion in the Yamato-75097 L6 chondrite: A preliminary examination
- Geology and geologic structure of the northern Ongul Islands and surroundings, East Antarctica
- Transverse Magneto-Conductivity of a Two-Dimensional Electron Gas
- Classification of several Yamato-75 chondrites (IV)
- Classification of several Yamato-75 chondrites (III)
- Theory of Hall Effect in a Two-Dimensional Electron System
- Relation of excess calcium accumulation to calcium-dependent apoptotic cell death in RCR-1 cells exposed to tributyltin
- ECONOMIC ASPECTS OF SOMATOFORM DISORDERS IN JAPAN
- Novel Statistical Classification Model of Type 2 Diabetes Mellitus Patients for Tailormade Prevention Using Data Mining Algorithm
- Prevalence and characteristics of chronic musculoskeletal pain in Japan
- Assessment of Workplace Air Concentrations of Indium Dust in an Indium-recycling Plant
- Knee Pain and Future Self-Reliance in Older Adults : Evidence From a Community-Based 3-Year Cohort Study in Japan
- Exposure Assessment of ETBE in Gas Station Workers and Gasoline Tanker Truck Drivers
- Increased Risk of Obesity Resulting from the Interaction between High Energy Intake and the Trp64Arg Polymorphism of the .BETA.3-adrenergic Receptor Gene in Healthy Japanese Men