Analysis of Urinary Metabolites of Polycyclic Aromatic Hydrocarbons in Incineration Workers
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概要
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Analysis of Urinary Metabolites of Polycyclic Aromatic Hydrocarbons in Incineration Workers: Masayoshi ICHIBA, et al. Department of Social and Environmental Medicine, Saga Medical School-Incineration workers are exposed to various pyrolysis products of organic materials, heavy metals and polycyclic aromatic hydrocarbons (PAHs). In this study, the exposure of incineration workers to PAHs was evaluated by measuring urinary metabolites of pyrene and naphthalene. The concentrations of urinary 1-hydroxypyrene(1OHP), a metabolite of pyrene, and 2-naphthol(2NP), a metabolite of naphthalene, were measured among 100 workers in 4 different types of incinerators, both before and after their work shifts. These incinerators were two old types, one modern type and one outdoors. The medians of urinary 10HP of before and after the work shifts obtained from all workers were 0.067 and 0.044μg/gCr, respectively; and the medians of urinary 2NP were 7.5 and 10.0μg/gCr, respectively. A significant increase of 2NP after the work shift was found at one old incinerator. A significant decrease of metabolites was found at the other old incinerator. Significant correlations were found between urinary metabolites and cigarettes smoked per day. The effect of smoking on urinary metabolite levels was also important. Significant correlations were found between urinary 10HP and 2NP levels in all workers. In multiple regression analysis smoking habit and incinerator type were found as significant factors. The improvement of the work environment, through decreasing exposure to both tobacco smoke and hazardous work shift-related substances, should be an occupational health aim.
- 社団法人日本産業衛生学会の論文
著者
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Horita Mikako
Department of Preventive Medicine, Faculty of Medicine, Saga University
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MATSUMOTO Yuki
Graduate School of Pharmaceutical Sciences, Kyushu University
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Horita Mikako
Dep. Of Preventive Medicine Fac. Of Medicine Saga Univ.
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Horita Mikako
Department Of Preventive Medicine Faculty Of Medicine Saga University
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MATSUMOTO Akiko
Department of Pediatrics, Kobato Gakuen, Aichi Human Service Center
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OGAWA Yasutaka
National Institute of Industrial Health
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小川 康恭
労働安全衛生総合研究所
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Yoshida Rie
National Institute Of Occupational Safety And Health
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Matsumoto Yuki
National Institute Of Occupational Safety And Health
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Matsumoto Yuki
Graduate School Of Pharmaceutical Sciences Kyushu University
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Tomokuni Katsumaro
Department of Social Medicine, Saga University
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小川 康恭
東京慈恵会医科大学環境保健医学教室
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ICHIBA Masayoshi
Department of Community Helth Science, Saga Medical College
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MOHRI Ippei
National Institute of Occupational Safety and Health, Saga Medical School
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KONDOH Toshihiro
Analytical Research and Experiment Center, Saga Medical School
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SAITO Hiroyuki
National Institute of Occupational Safety and Health, Saga Medical School
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OHBA Ken-ichi
National Institute of Occupational Safety and Health, Saga Medical School
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YAMASHITA Zenkoh
Department of Social and Environmental Medicine, Saga Medical School
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Ohba Ken-ichi
北里大学 医療衛生学部衛生管理学
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Mohri Ippei
National Institute Of Occupational Safety And Health Saga Medical School
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Ohba Ken-ichi
National Institute Of Occupational Safety And Health Saga Medical School
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Ichiba Masayoshi
Department Of Social And Environmental Medicine Saga Medical School
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Ichiba Masayoshi
Department Of Community Helth Science Saga Medical College
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Kondoh Toshihiro
Analytical Research And Experiment Center Saga Medical School
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Tomokuni Katsumaro
Department Of Social And Environmental Medicine Saga Medical School
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Tomokuni Katsumaro
Department Of Community Health Science Saga Medical School
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Matsumoto Akiko
Department Of Social And Environmental Medicine Saga Medical School
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Matsumoto Akiko
Department Of Food Science Kyoto Women's University
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Saito Hiroyuki
National Institute Of Occupational Safety And Health Saga Medical School
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Saito Hiroyuki
National Inst. Of Occupational Safety And Health
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Yamashita Zenkoh
Department Of Social And Environmental Medicine Saga Medical School
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Ichiba Masayoshi
Department of Community Health Science, Saga Medical School
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