THE IN VITRO EFFECT OF 13 METALS ON THE ACTIVITY OF ERYTHROCYTE PYRIMIDINE 5'-NUCLEOTIDASE (P5N)
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概要
- 論文の詳細を見る
The in vitro effect of 13 metal ions on the activity of erythrocyte pyrimidine 5'-nucleotidase (P5N) was investigated. Particular metals belonging to the boron group have recently been used as materials in a semi-conductor manufacturing. Of these metal ions, Ga exhibited no inhibition of erythrocyte P5N, while In extensively inhibited the erythrocyte P5N activity at concentrations of 10^<-4> to 10^<-3> M. In addition, the activity of erythrocyte P5N was inhibited by 90-96% when the metal ions such as Cu, Ag, Cd, Hg or Pb were added to the incubation mixture at concentrations of 10^<-4> to 10^<-3> M. On the other hand, there was no difference between sulfate and nitrate in the in vitro effect of the metal ions on the activity of erythrocyte P5N.
- 日本トキシコロジー学会の論文
- 1994-11-30
著者
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OISHI Hirotaka
Space Utilization Research Center, National Space Development Agency of Japan (NASDA)
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Oishi Hirotaka
Department Of Community Health Science Saga Medical School
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Ichiba M
Dep. Of Social And Environmental Medicine Saga Medical School
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Ichiba Masayoshi
Department Of Community Helth Science Saga Medical College
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Tomokuni Katsumaro
Dep. Of Social And Environmental Medicine Saga Medical School
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Tomokuni Katsumaro
Department Of Community Health Science Saga Medical School
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Ichiba Masayoshi
Department of Community Health Science, Saga Medical School
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- THE IN VITRO EFFECT OF 13 METALS ON THE ACTIVITY OF ERYTHROCYTE PYRIMIDINE 5'-NUCLEOTIDASE (P5N)