INTERACTION OF ZINC AND OTHER METAL ON THE ACTIVITY OF ERYTHROCYTE δ=AMINO-LEVULINIC ACID DEHYDRATASE IN VITRO
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概要
- 論文の詳細を見る
The interaction of zinc and other metal such as lead, mercury (II), cadmium, silver (II) on the activity of erythrocyte δ-aminolevulinic acid dehydratase (ALA-D) was investigated in vitro. At the concentrations ranging from 0.01 to 1.0 mmol/l, lead, mercury (II), cadmium and silver (II) strikingly inhibited the erythrocyte ALA-D activity. The in vitro addition of zinc having an activating effect for the erythrocyte ALA-D, was observed to eliminate the lead-induced inhibition of the erythrocyte ALA-D activity. And the degree of the elimination seemed to depend on the molar ratio (Zn/Pb) of both metal concentrations in the ALA-D assay. However, the inhibition of erythrocyte ALA-D activity caused by mercury (II), cadmium and silver (II) was not removed by the in vitro addition of zinc.
- 日本トキシコロジー学会の論文
- 1979-02-15
著者
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Tomokuni Katsumaro
Department of Social Medicine, Saga University
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Tomokuni Katsumaro
Department Of Community Health Science Saga Medical School
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Tomokuni Katsumaro
Department Of Public Health Okayama-university Medical School
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