The Stability of the Oxidative Stress Marker, Urinary 8-hydroxy-2'-deoxyguanosine (8-OHdG), when Stored at Room Temperature
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概要
- 論文の詳細を見る
We examined the stabilities of urinary 8-hydroxy-2'-deoxyguanosine (8-OHdG) stored at room temperature (25℃) for 24 h or at -80℃ for 800 days. Subjects were 19 males and 17 females aged 23-58 yr for the 24-h study, and 9 males and 4 females aged 24-54 yr for the 800-day study. We obtained information on the subjects by questionnaires and interviews. The level of urinary 8-OHdG was measured by HPLC using two-step separations. There were no significant changes of amount of urinary 8-OHdG under either storage conditions. We conclude that urine samples can be stored at 25℃ and below for 24 h, when the research purpose includes the determination of urinary 8-OHdG. Urinary 8-OHdG was also stable for over two years when stored at -80℃.
- 社団法人日本産業衛生学会の論文
著者
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MATSUMOTO Yuki
Graduate School of Pharmaceutical Sciences, Kyushu University
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Ohta Hisayoshi
Graduate School Of Medical Science Kitasato University
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Kasai Hiroshi
Department of Environmental Oncology, Institute of Industrial Ecological Sciences, University of Occ
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OGAWA Yasutaka
National Institute of Industrial Health
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小川 康恭
労働安全衛生総合研究所
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Kasai Hiroshi
Department Of Environmental Oncology University Of Occupational And Environmental Health
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Kasai Hiroshi
Department Of Ennvironmental Oncology Institute Of Industrial Ecological Sciences
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Yoshida Rie
National Institute Of Occupational Safety And Health
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Matsumoto Yuki
National Institute Of Occupational Safety And Health
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Matsumoto Yuki
Graduate School Of Pharmaceutical Sciences Kyushu University
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小川 康恭
東京慈恵会医科大学環境保健医学教室
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SHIMAMORI Ayako
School of Allied Health Sciences, Kitasato University
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Shimamori Ayako
School Of Allied Health Sciences Kitasato University
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