RELATIONSHIP BETWEEN TUBERCULIN REACTION AND FERNANDEZ'S REACTION CAUSED BY DHARMENDRA'S ANTIGEN AMONG GENERAL POPULATION:Report III: Re-investigation in T-Town
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The results reported in the previous papers dealing with the correlation between the tuber culin reaction and Fernandez's reaction caused by Dharmendra's antigen among the general population of four towns and one village have shown that the difference between the positive rates of both reactions was influenced mainly by age and it was suggested that the BCG-vaccination gave much more influence upon the positive rate of reaction to Dharmendra's antigen than the tuberculous infection.<BR>In this paper the analytical studies of the re-investigation results in T-Town were presented on these two reactions according to the history of BCG-vaccination among 4, 779 inhabitants who were primarily investigated in 1960. The results obtained were as follows;<BR>1) The average positive rate to Dharmendra's antigen was 49.0% in the BCG-vaccinated and 34.4% in the unvaccinated cases, while that of tuberculin reaction was 57.7% in the former and 78.2% in the latter, respectively. The difference between the positive rates of these two reactions was bigger in the former than in the latter.<BR>2) The correlation between the size of reaction to Dharmendra's antigen and that of tuberculin reaction was higher in the BCG-vaccinated cases than in the unvaccinated. The positive rate to Dharmendra's antigen among the tuberculin positive cases was obviously higher in the former (74.1%) than in the latter (41.0%). Namely, the positive reaction caused by Dharmendra's antigen tend to appear more often in the BCG-vaccinated cases than in the un vaccinated.<BR>3) The frequency distribution curves of the positive rates of both reactions by age group in T-Town inhabitants ware analysed according to the history of BCG-vaccination. It was revealed that the distribution curves in the unvaccinated cases was quite similar to those of S-Village inhabitants in the first report. Accordingly, the difference observed in the frequency distribution curves of four towns in the second report was assumed to be caused by the influence of BCG-vaccination carried out on the certain age group with different extent.
- 一般社団法人 日本結核病学会の論文
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