A case of adenoid cystic carcinoma which resulted in local recurrence and brain metastasis 13 years later.

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A 73-year-old female was admitted to our hospital with a complaint of left temporal swelling. She had a history of gingival adenoid cystic carcinoma in 1967, and was operated for left maxillary cancer including a partial resection with left selective lymphnode resection. Radium needle application was done against recurrence at that time. After these treatments, she was cancer free until November, 1980.<BR>Pathological examination showed recurrence in the gingiva around maxillary defect. CT scan revealed that the tumor proliferated from the maxilla to the left temporal region. It was suspected that it has mestasted to brain. Chemoserapy using adriamycin and mitomycin C, and x-ray irradiation therapy had been done effectively. The tumor in the temporal region decreased in size after these therapies.<BR>We reported a case of adenoid cystic carcinoma that recurred 13 years after the first treatment. The pertinent literature was reviewed and the clinical procedure discussed.
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