顎・口腔疾患患者に対しての扁平上皮癌関連抗原TA-4 (SCC抗原) の検索

概要

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Squamous cell carcinoma related antigen TA-4 (SCC-Ag) was examined by radio immunoassay in 33 patients with oral and maxillofacial lesions. In nine of 10 patients with untreated malignant tumors, there were detected high positive levels of antigen. The average data of them showed 2.97 ± 1.09 ng/ml. After treatment, 12 patients who had no recurrences or metastasis showed relatively low positive levels, such as the average of 2.31 ± 0.83 ng/ml. However, in benign tumors, cysts and other diseases with the exception of malignant tumors, there were detected lower than standard levels (2.0 ng/ml) or TA-4. TA-4 (SCC-Ag) appears useful for diagnosing and monitoring to learn the recurrence of metastasis of patients with oral and maxillofacial malignant tumors.