口腔外科領域各種感染症に対するセブブペラゾン (CBPZ, ケイペラゾン) の臨床使用成績

概要

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Clinical evaluation of Cefbuperazone (CBPZ) in 63 cases of various infections inthe oro-facial region was carried out. Bacteria were isolated from the infectious lesions and their sensitivity to Cefbuperazone was tested. The results are summarized as follows.<BR>1. CBPZ was subjectively evaluated by doctors who used the drug, and considered excellent in 20 cases, good in 32 cases, fair in 6 cases and poor in 5 cases, the effectiveness rate being 82. 5%. On the other hand, CBPZ was also estimated by way of a scoring system evaluation and considered excellent in 15 cases, good in 37 cases and poor in 11 cases, the effectiveness rate being 82. 5%.<BR>2. Bacteria were able to be isolated in 57 cases (90. 5%). Of the isolated 90 strains, 21 were anaerobic (23. 3%). These isolated anaerobics were highly sensitive to CBPZ.<BR>3. No remarkable side effect was observed, but elevation of S-GOT in one case, S-GPT in two cases and ESR in two cases were observed.<BR>According to these results, CBPZ was evaluated to be useful antibiotics for various infections in the field of oral surgery.