肺から転移したと思われる下顎歯肉小細胞癌の1例

概要

論文の詳細を見る
Small cell carcinomas usually occur in the lung, and they often metastasize to the brain. We encountered a case of small cell lung cancer (SCLC) which apparently metastasized to the oral region. The patient was a 50-year-old man with a tumor in the mandibular gingiva which was suspected to be the primary lesion. Pathologically, it was diagnosed to be a small cell carcinoma, because round or short spindleshaped cells were observed using hematoxylin-eosin stain, and the NSE (neuron specific enolase) immunohistochemical staining method was positive. Chest X-ray examination, CT scan and scintigraphy indicated the presence of in the right upper pulmonary lobe. As SCLC rarely occurs in the oral region, the oral lesion was considered to have originated in the lung. However, the diagnosis could not be confirmed because biopsy of the lung tumor was impossible. The patient died due to septicemia 3 months after admission.
社団法人日本口腔外科学会の論文