THE VIRULENCE TEST OF POLIVIRUSES USING THE PRIMARY HUMAN AMNION CELL AND THE EFFECTS OF THEIR INTRASPINAL INJECTION TO MICE
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概要
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The virulent tests on polioviruses not only afford the important means for investigating their variation and heredity, but especially need examination of the recovery of virulence which might possibly be brought about by passing through the human body. The virulence test using monkeys has been widely recognized as the best method, but it is followed by economic and technical difficulties. In order to eliminate such difficulties, several methods have been proposed for the in vitro marker test.The present paper deals with a new in vitro method for virulence tests on polioviruses by using the primary human amnion cell, with the result of intraspinal injection of polioviruses into mice.
- 久留米大学医学部 The Kurume Medical Journal 編集部の論文
著者
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Kuroda Kenji
Department Of Fermentation Technology Faculty Of Engineering Hiroshima University
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Yamamoto Shigeru
Department Of Biology Faculty Of Science Kyushu University
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KURODA KENJI
Department of Microbiology, Kurume University School of Medicine
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Shingu M.
Department of Microbiology, Kurume University School of Medicine
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