MUTANTS OF HERPES SIMPLEX VIRUS:II. IDU-RESISTANT MUTANTS AND A PRELIMINARY EXPERIMENT ON GENETIC RECOMBINATION
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概要
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The IDU (5-iodo-2'-deoxyuridine)-resistant mutants (SI, LI and GI) obtained from S (small plaque f ormers), L (large plaque f ormers) and G (polykaryocyte formers) of herpes simplex virus have a similar character in antigenicity and the same heat stabilty as the originl types of viruses. Mixed infection with SI and L produced a recombinant virus at relatively high frequencies. In the mixed infection with SI and G, unexpected recombinant types such as L and LI were produced in addition to GI recombinant. This suggests that G character may be determined by a combination of at least two cistrons which exhibit the L character when they function separately.
- 久留米大学医学部 The Kurume Medical Journal 編集部の論文
著者
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Yamamoto Shigeru
Department Of Biology Faculty Of Science Kyushu University
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SUENAGA YOSHITAKA
Department of Microbiology, Kurume University School of Medicine
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KABUTA HIROFUMI
Department of Microbiology, Kurume University School of Medicine
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