Nutrition during Pregnancy May Be Associated with Allergic Diseases in Infants

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概要

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• The prevalence of allergic diseases is high in Japan, even in infants. Their risk for developing allergies is influenced by the antigens in the mothers diet during pregnancy. We hypothesized that, apart from the antigens, hypersensitivity induced through high energy and nutrient intake by mothers during pregnancy may be a factor for allergic diseases in their babies. In this study, we tried to confirm our hypothesis. Allergy histories of parents and their infants, body characteristics and food and nutrient intake were measured by a questionnaire and a food frequency questionnaire, respectively. A total of 2, 642 responses were obtained (return rate, 94.7%). The major allergic diseases in the infants were atopic dermatitis (6.0%), food allergy (3.7%) and bronchial asthma or asthmatic bronchitis (3.2%). About 60% of the infants with allergies had a family history of allergies. Family his-tory of allergy, age of infant, order of birth, head and chest circumferences of infants, BMI of mothers before pregnancy and delivery and intake of lipids (fat and vegetable oil) and vegetables by mothers related positively, and the intake of protein, carbohydrates and milk and its products correlated negatively with allergic diseases in the infants (p<0.05). The results, together with previous reports, suggest that a high intake of energy and lipids (fat and vegetable oil) during pregnancy may accelerate allergic diseases in infants.

• 財団法人 学会誌刊行センターの論文
• 2002-10-01

著者

• Katoh Masahiko

  日本大学医学部附属駿河台病院 循環器科

• Kawashiri Masa-aki

  金沢大学 医学系研究科循環医科学専攻

• Sakai Kentaro

  Department Of Environmental Science Faculty Of Human Life Science Hiroshima Jogakuin University

• Matsumoto Kenji

  National Res. Inst. Child Health & Dev. Tokyo Jpn

• Wakiguchi Hiroshi

  Department Of Pediatrics Kochi Medical School

• Wakiguchi Hiroshi

  Department Of Pediatrics Kohchi Medical School

• Matsumoto Kenji

  Department Of Allergy And Immunology National Research Institute For Child Health And Development

• Shinohara Miwa

  Department Of Pediatrics Kochi Medical School

• Sakai K

  Department Of Anatomy Hokkaido University School Of Medicine

• Komatsu T

  Department Of Earth Sciences Kumamoto University:nanjing Institute Of Geology And Palaeontology Chin

• Komatsu Tatsushi

  Department Of Clinical Nutrition Faculty Of Comprehensive Rehabilitation Osaka Prefecture University

• Ushiyama Yuh

  Department Of Nutrition School Of Medicine The University Of Tokushima

• Sakai K

  Department Of Nutrition School Of Medicine The University Of Tokushima

• Matsumoto Kenji

  Department Of Allergy And Immunology National Institute For Child Health & Development

• Yamamoto S

  Department Of Applied Chemistry Graduate School Of Engineering Osaka City University (ocu)

• Yamamoto Shigeru

  Department Of Nutrition School Of Medicine The University Of Tokushima

• Yamamoto Shigeru

  Department Of Biology Faculty Of Science Kyushu University

• Komatsu T

  Department Of Nutrition And Food Science Faculty Of Human Life And Environmental Science Ochanomizu

• Wakiguchi H

  Department Of Pediatrics And Adolescence Kochi Medical School

• Matsumoto Kenji

  Department of Allergy & Immunology, National Research Institute for Child Health and Development

• Shinohara Miwa

  Department of Pediatric Allergy and Clinical Research, National Shimosizu Hospital:Department of Pediatrics, Kochi University

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