Genetic Variations of CYP2C9 in 724 Japanese Individuals and Their Impact on the Antihypertensive Effects of Losartan
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概要
- 論文の詳細を見る
- 2008-08-01
著者
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SAITO Yasushi
Chiba University
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KAWANO Yuhei
National Cardiovascular Center
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NAKAO Kazuwa
Kyoto University
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HORIO Takeshi
National Cardiovascular Center
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Takishita S
University Of The Ryukyus
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KOKUBO Yoshihiro
Department of Preventive Cardiology, National Cardiovascular Center
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Naritomi Hiroaki
Division Of Cardiology National Cardiovascular Center
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Nakagami Hironori
Division Of Gene Therapy Science Osaka University Graduate School Of Medicine
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SAWADA Jun-ichi
Project Team for Pharmacogenetics, National Institute of Health Sciences
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喜多 義邦
Division Of Preventive Cardiology National Cardiovascular Center
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Kawamoto Manabu
国立医薬品食品衛生研究所
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Kawamoto Manabu
Division Of Genomic Medicine Department Of Advanced Biomedical Engineering And Science Tokyo Women&a
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Kawamoto Manabu
Institute Of Rheumatology Tokyo Women's Medical University
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Yoshida S
Chiba University
-
Miyashita K
Department Of Cardiovascular Surgery National Cardiovascular Center
-
Nonogi Hiroshi
Cardiology And Emergency Medicine National Cardiovascular Center
-
Kotani Yasushi
国立循環器病センター 予防検診
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Yoshida Akio
鳥取大学 医学部遺伝子再生医療学講座
-
Harada Takashi
Division Of Nephrology Clinical Research Center National Kyushu Medical Center
-
Kawano Yuhei
Division of Hypertension and Nephrology, National Cardiovascular Center
-
Koseki Masahiro
大阪大学 医学系研究科循環器内科学
-
Saito Y
Department Of Cardiovascular Medicine Osaka University Graduate School Of Medicine
-
Sawada Junichi
Project Team For Pharmacogenetics National Institute Of Health Sciences
-
Maekawa Keiko
Project Team For Pharmacogenetics National Institute Of Health Sciences
-
Maekawa Keiko
Division Of Drug Evaluation National Institute Of Health Sciences Osaka Branch
-
Yoshida Akio
Tokyo Medical University
-
Kawano Yuhei
国立循環器病センター 高血圧腎臓内科
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Kawano Yuhei
Division Of Hypertension And Nephrology National Cardiovascular Center
-
Kamide Kei
Division Of Hypertension And Nephrology Department Of Medicine National Cardiovascular Center
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Horio Takeshi
国立循環器病センター 高血圧腎臓内科
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Nakao Kazuwa
大阪府立病院機構大阪府立急性期総合医療センター
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Nakao Kazuwa
国立病院機構京都医療センター 代謝臨床研究センター内分泌研究部
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Miyata Toshiyuki
Research Institute National Cardiovascular Center
-
SAITO Yoshiro
Division of Biochemistry and Immunochemistry, National Institute of Health Sciences
-
SAWADA Jun-ichi
Division of Biochemistry and Immunochemistry, National Institute of Health Sciences
-
Kitakaze Masafumi
Division Of Cardiology National Cardiovascular Center
-
Kitakaze Masafumi
国立循環器病センター 心臓血管
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Kitakaze Masafumi
Nagoya University Graduate School Of Medicine
-
Tomoike Hitonobu
Division Of Preventive Cardiology National Cardiovascular Center
-
Tomoike Hitonobu
国立循環器病センター 疫学部
-
Tomoike Hitonobu
国立循環器病センター研究所 疫学部
-
Tomoike Hitonobu
Department of Cardiology, National Cardiovascular Center
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Takahashi Hakuo
Department Of Cardiovascular Medicine Shinshu University Graduate School Of Medicine
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Muro K
国立がんセンター中央病院
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Muro Kei
Gastrointestinal Oncology Division National Cancer Center Hospital
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Niki Hisae
国立がんセンター中央病院 消化器内科
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Kaneda Yasufumi
Division Of Gene Therapy Science Osaka University
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SARUTA Takao
Saruta Dermatology Clinic
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Takishita Shuichi
琉球大学医学部附属病院 血液浄化療法部
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Yoshida Shigeaki
国立がんセンター東病院 消化管内科
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Manabe Kasumi
鳥取大学 医学系研究科再生医療学
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Miyatake Kunio
国立病院機構大阪南医療センター 循環器科
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MINATOYA Kenji
National Cardiovascular Center
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Kitakaze Masafumi
Division Of Cardiovascular Medicine National Cardiovascular Center
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Nakao K
Department Of Medicine And Medical Science Kyoto University Graduate School Of Medicine
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Matsuura Kaoru
国立循環器病センター
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Sawada Jun-ichi
Division Of Functional Biochemistry And Genomics National Institute Of Health Sciences
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HANADA Hironori
Research Institute, National Cardiovascular Center
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TAKIUCHI Shin
Division of Hypertension and Nephrology, National Cardiovascular Center
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HORIO Takeshi
Division of Hypertension and Nephrology, National Cardiovascular Center
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Kawano Yuhei
Division Of Hypertension And Nephrology Department Of Internal Medicine National Cardiovascular Cent
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Kobayashi Yoshio
Cardiovascular Division National Cardiovascular Center
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Tomoike H
Division Of Preventive Cardiology National Cardiovascular Center
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Nakahama Hajime
Division Of Hypertension And Nephrology National Cardiovascular Center
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Morisaki Takayuki
国立循環器病センター 心臓血管内科
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Morisaki Takayuki
Department Of Biosciences Research Institute National Cardiovascular Center
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Katanosaka Yuki
国立循環器病センター
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Honda Takeshi
Department Of Hypertension And Cardiorenal Medicine Dokkyo University School Of Medicine
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喜多 義邦
島根大学 医学部環境保健医学講座公衆衛生学
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YIN Tong
Research Institute, National Cardiovascular Center
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MIYASHITA Kotaro
Cerebrovascular Division, Department of Medicine, National Cardiovascular Center
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AKAIWA Yasuhisa
Cerebrovascular Division, Department of Medicine, National Cardiovascular Center
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OTSUBO Ryoichi
Cerebrovascular Division, Department of Medicine, National Cardiovascular Center
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NAGATSUKA Kazuyuki
Cerebrovascular Division, Department of Medicine, National Cardiovascular Center
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OTSUKI Toshiho
Cerebrovascular Division, Department of Medicine, National Cardiovascular Center
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MINEMATSU Kazuo
Cerebrovascular Division, Department of Medicine, National Cardiovascular Center
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NARITOMI Hiroaki
Cerebrovascular Division, Department of Medicine, National Cardiovascular Center
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SASAKI Yasutsuna
National Cancer Center Hospital East
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Nakao Kazuwa
奈良県立医科大学 内科学第一
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Nakao Kazuwa
Division Of Endocrinology And Metabolism Department Of Medicine And Clinical Science Kyoto Universit
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Nakagami Hironori
Division Of Clinical Gene Therapy Osaka University Graduate School Of Medicine
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Obara Taku
東北大学 臨床薬学
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Katoh Masahiko
日本大学医学部附属駿河台病院 循環器科
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Hayashi Hiroki
Department Of Geriatric Medicine And Nephrology Osaka University Graduate School Of Medicine
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Kosakai Yoshio
Department Of Cardiovascldar Surgery National Cardiovascudar Center
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Okuda Tomohiko
国立循環器病センター研究所 疫学部
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Kitakaze Masafumi
大阪大学 第1内科
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Takagi Shuichi
国立循環器病センター
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Kawashiri Masa-aki
金沢大学 医学系研究科循環医科学専攻
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Minatoya Kenji
国立循環器病センター 心臓血管外科
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Hanada Hironori
Research Institute National Cardiovascular Center
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Minematsu Kazuo
Cerebrovascular Division Department Of Medicine National Cardiovascular Center
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Minematsu Kazuo
Infomatics Science Nara Institute Of Science And Technology
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Minematsu Kazuo
Cerebrovascular Division Department Of Internal Medicine National Cardiovascular Center
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Miyashita Kotaro
Cerebrovascular Division Department Of Medicine National Cardiovascular Center
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Yin Tong
Research Institute National Cardiovascular Center
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Miyata Toshiyuki
Department Of Clinical Gene Therapy Osaka University Graduate School Of Medicine
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Tanaka H
Department Of Urology Kawasaki Medical School
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Saito Yoshiro
Division Of Gastrointestinal Oncology National Cancer Center Hospital
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Kato Norihiro
Department Of Gene Diagnostics And Therapeutics Research Institute International Medical Center Of J
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Kajikawa Mariko
ABLE Corporation
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Kitakaze Masafumi
Department Of Cardiovascular Medicine National Cardiovascular Center
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Morisaki T
Department Of Bioscience National Cardiovascular Center Research Institute
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Saito Yoshiro
Division Of Biochemistry And Immunochemistry National Institute Of Health Science
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Takahashi Hakuo
Clinical Laboratory Medicine Kansai Medical University
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Maekawa Keiko
Division Of Biochemistry And Immunochemistry National Institute Of Health Sciences
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Sawada Jun-ichi
Division Of Biochemistry And Immunochemistry Natinal Institute Of Health Sciences
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Horio Takeshi
Division Of Hypertension And Nephrology Department Of Medicine National Cardiovascular Center
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Saruta Takao
The Department Of Internal Medicine Keio University School Of Medicine
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Otsubo Ryoichi
Cerebrovascular Division Department Of Medicine National Cardiovascular Center
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Takiuchi Shin
Division Of Cardiology Higashi-takarazuka Sato Hospital
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Kokubo Yoshihiro
Department Of Cardiology National Cardiovascular Center
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Kokubo Yoshihiro
Cardiovascular Division National Cardiovascular Center
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NAKAMURA Kenjiro
Tenjin Sogo Clinic
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Tomoike Hitonobu
Department Of Cardiology National Cardiovascular Center
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Tomoike Hitonobu
National Cardiovasular Center
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Tomoike Hitonobu
Cardiovascular Division Of Internal Medicine National Cardiovascular Center
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HARADA Takashi
Ministry of Health and Welfare of Japan and Japanese Society of Nephrology
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Ojima Toshiyuki
Hamamatsu Univ. School Of Medicine
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Okubo Takayoshi
Department Of Planning For Drug Development And Clinical Evaluation Tohoku University
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Harada Takehiko
Department Of Internal Medicine Tokushima University
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Saruta Takao
Department Of Clinical Pharmacology Jichi Medical School
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Saruta Takao
Fukuoka University School Of Medicine
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Miyatake Kunio
Department Of Cardiology National Cardiovascular Center
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Yamamoto S
Biometric Research Section Statistics And Cancer Control Division Research Center For Cancer Prevent
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Kammatsuse Katsuo
Nihon University
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Nakamura Kazuyo
Department Of Preventive Medicine Faculty Of Medicine Saga University
-
Kakihara Masako
Division Of Cardiology Department Of Internal Medicine National Cardiovascular Center
-
Takiuchi Shin
Division Of Hypertension And Nephrology National Cardiovascular Center
-
Takano Makoto
Division Of Molecular Physiology And Biophysics Department Of Physiology Jichi Medical University
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Takano M
Division Of Biophysics Department Of Physiology Jichii Medical School
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Kakeji Yosihiro
九州大学 医学研究院消化器･総合外科
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Kawamura Mihoko
Department Of Cardiovascular And Respiratory Medicine Shiga University Of Medical Science
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Yoshita Katsushi
Project For The National Health And Nutrition Survey National Institute Of Health And Nutrition
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Manabe Kasumi
Division Of Cardiovascular Medicine National Cardiovascular Center
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Tochikubo Osamu
The Second Department Of Internal Medicine Yokohama City University
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Okura Takafumi
Department Of Planning For Drug Development And Clinical Evaluation Tohoku University
-
Tomoike Hitonobu
Able Corporation:department Of Biotechnology School Of Engineering Nagoya University
-
Tomoike Hitonibu
Department Of Cardiology National Cardiovascular Center
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Kadoshima Yoko
Department Of Public Health Kanazawa Medical University
-
Kaneko Yoshihiro
The Second Department Of Internal Medicine Yokohama City University School Of Medicine
-
Naritomi Hiroaki
Cerebrovascular Division Department Of Medicine National Cardiovascular Center
-
Koga Masatoshi
Cerebrovascular Division Department Of Medicine National Cardiovascular Center
-
Mannami Toshifumi
Department Of Preventive Cardiology National Cardiovascular Center
-
Tanaka Shigemichi
The Second Department Of Internal Medicine Sapporo Medical College
-
Nagatsuka Kazuyuki
The Cerebrovascular Division Department Of Medicine National Cardiovascular Center
-
Nagatsuka Kazuyuki
Cerebrovascular Division Department Of Medicine
-
Saito Yasushi
Department Of Clinical Cell Biology Chiba University Graduate School Of Medicine
-
Kosakai Yoshio
National Cardiovascular Center
-
Sawada J
Mie Univ. School Of Medicine Mie Jpn
-
Sano Toshio
2nd Department Of Internal Medicine School Of Medicine Yokohama City University
-
Akie Yasuki
Cerebrovascular Division Department Of Medicine National Cardiovascular Center
-
Takiuchi Shin
Department Of Molecular Cardiology Osaka University Graduate School Of Medicine
-
Kamide Kei
Division Of Cardiovascular Medicine Department Of Medicine School Of Medicine Jichi Medical Universi
-
Kuzuya Masafumi
Department Of Geriatrics Nagoya University Graduated School Of Medicine
-
Saitoh Yoshihiko
The Department Of Medicine And Clinical Science Kyoto University Graduate School Of Medicine
-
Tamaki Shinji
Department Of Cardiology Shiga University Of Medical Science
-
Tamaki Shinji
Division Of Cardiology Department Of Medicine Shiga University Of Medical Science
-
Shindo Tadashi
2nd Department Of Internal Medicine School Of Medicine Yokohama City University
-
Miyata Toshiyuki
Department Of Preventive Cardiology National Cardiovascular Center:hygiene And Public Health Social
-
Shinomura Yasuhisa
Cardiovascular Medicine Department Of Internal Medicine Osaka University Graduate School Of Medicine
-
Sasaki Tamaki
Division Of Nephrology And Rheumatology Department Of Internal Medicine Kawasaki Medical School
-
Yamamoto Akira
Cerebrovascular Division Department Of Medicine National Cardiovascular Center
-
Tomoike Hitonobu
Division Of Cardiovascular Medicine National Cardiovascular Center
-
Manabe Kasumi
Division Of Regenerative Medicine And Therapeutics Department Of Gene Therapy And Regenerative Medic
-
Ogihara T
Osaka Univ. Medical School Osaka Jpn
-
Nonogi Hiroshi
Dep't Of Cardiology National Cardiovascular Center
-
Horiguchi Takashi
Department Of Neurosurgery Keio University School Of Medicine
-
Nakao Kazuwa
The Department Of Medicine And Clinical Science
-
Honda Toshihiro
Saiseikai Kumamoto Hospital
-
Shigihara Toshikatsu
Keio Univ. School Of Medicine
-
Hanasaki Hiroko
Department Of Geriatric Medicine And Nephrology Osaka University Graduate School Of Medicine
-
Sawada J
National Inst. Of Health Sci. Tokyo Jpn
-
Horio Takeshi
Divisions Of Hypertension And Nephrology National Cardiovascular Center
-
Kitakaze Masafumi
First Department Of Medicine And Department Of Pathophysiology Osaka University School Of Medicine
-
Susawa Takashi
Third Division Internal Medicine Faculty Of Medicine Kyoto University
-
Saito Y
Division Of Biochemistry And Immunochemistry National Institute Of Health Sciences
-
Akaiwa Yasuhisa
Cerebrovascular Division Department Of Medicine National Cardiovascular Center
-
Harada Takehiko
1st. Dept Of Intern. Med. Tokushima Univ. School Of Med.
-
Kadoma Masaaki
First Department Of Medicine And Department Of Pathophysiology Osaka University School Of Medicine
-
Kuwahara Koichiro
Department Of Medicine And Clinical Sciences Graduate School Of Medicine Kyoto University
-
Takeda Hideo
Department Of Preventive Medicine Institute Of Health Biosciences The University Of Tokushima Gradua
-
Tanaka Hiroyoshi
Department Of Urology Kawasaki Medical School
-
Nonogi Hiroshi
Department Of Cardiology Medical School Osaka University
-
Nonogi Hiroshi
Division Of Cardiac Care Unit Department Of Cardiovascular Medicine National Cerebral And Cardiovasc
-
Nonogi Hiroshi
Division Of Cardiovascular Medicine National Cardiovascular Center
-
TOMOIKE Hitonobu
Sakakibara Heart Institute
-
Morisaki Takayuki
Department Of Medicine University Of Pennsylvania
-
Honda Takeshi
The Department Of Hypertension And Cardiorenal Medicine Dokkyo University School Of Medicine
-
Kangawa Kenji
National Cerebral And Cardiovascular Center Research Institute
-
Sasaki Yasutsuna
Division Of Hematology And Oncology National Cancer Center Hospital East
-
Miyake Takashi
Division Of Clinical Gene Therapy Osaka University Graduate School Of Medicine
-
Hagino Takeshi
Divisions Of Hypertension And Nephrology National Cardiovascular Center
-
Horie Takashi
Department Of Cardiovascular Medicine Shinshu University Graduate School Of Medicine
-
Kadoma Masaaki
The First Department Of Medicine Osaka University School Of Medicine
-
Yoshida Sho
Department Of Internal Medicine Komagome Hospital
-
Kato Norihiro
Graduate School Of Human And Environmental Studies University Of Kyoto
-
Miura Toshie
Department Of Ophthalmology Hokkaido University Graduate School Of Medicine
-
Nagatsuka Kazuyuki
Department Of Medicine And Clinical Sciences Graduate School Of Medicine Kyoto University
-
Horio Takeshi
Division Of Hypertension And Nephrology
-
Kamide Kei
Division Of Cardiovascular Medicine Department Of Medicine Jichi Medical University School Of Medicine
-
Hirose Takuo
Department Of Preventive And Public Health Dentistry Fukuoka Dental Colledge
-
Hayashi Norihiro
Department Of Clinical Pharmacology And Pharmacogenomics Graduate School Of Pharmaceutical Sciences Osaka University
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- Adipocytokines as new promising markers of colorectal tumors : Adiponectin for colorectal adenoma, and resistin and visfatin for colorectal cancer
- Safety of irinotecan and infusional fluorouracil/leucovorin (FOLFIRI) in Japan : a retrospective review of 48 patients with metastatic colorectal cancer
- The Novel Compounds That Activate Farnesoid X Receptor : the Diversity of Their Effects on Gene Expression
- 5 The Japanese Primary Prevention of Atherosclerosis with Aspirin for Diabetes (JPAD)(Late Breaking Clinical Trials I,The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- Improvement of Quality of Life With Nocturnal Oxygen Therapy in Heart Failure Patients With Central Sleep Apnea
- PJ-106 Interleukin-6 as an Independent Predictor of Future Cardiovascular Events in Patients with Cardiovascular Risk Factors(Growth factor/Cytokine(02)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- Detection of colorectal cancer cells from feces using quantitative real-time RT-PCR for colorectal cancer diagnosis
- Dual Gradient-echo In-phase and Opposed-phase Magnetic Resonance Imaging to Evaluate Lipomatous Metaplasia in Patients with Old Myocardial Infarction
- Autophagy is activated in pancreatic cancer cells and correlates with poor patient outcome
- Rectosigmoid Cancer with Widespread Scrotal and Perineal Abscesses Successfully Resected by Total Pelvic Exenteration : Case Report
- Wound Infection After a Laparoscopic Resection for Colorectal Cancer
- Contrast-enhanced ultrasonography with Sonazoid for evaluation of renal microcirculation
- Prognosis of Hypercholesterolemic Patients Taking Pravastatin for Five Years : The Chiba Lipid Intervention Program(CLIP) Study
- CHARACTERIZATION OF `MIDBAND' LIPOPROTEINS AS A RISK FACTOR OF ISCHEMIC HEART DISEASE : Arteriosclerosis : 53 Annual Scientific Meeting, Japanese Circulation Society
- Significance of a Polymorphism(G->A transition) in the-75 Position of the Apolipoprotein A-1 Gene Promoter on Serum High Density Lipoprotein-Cholesterol Levels in Japanese Hyperlipidemic Subjects
- evidence-based practice guideline for the treatment of chronic kidney disease
- Genetic Polymorphisms of Copper- and Platinum Drug-efflux Transporters ATP7A and ATP7B in Japanese Cancer Patients
- Ethnic Differences of two Non-synonymous Single Nucleotide Polymorphisms in CDA Gene
- Long-term (14 years) Effect of LDL Apheresis on Obstructive Changes in Aortocoronary Saphenous-vein Bypass Grafts in a Case of Heterozygous Familial Hypercholesterolemia with the LDL Receptor Proline^ to Leucine Mutation
- A Clinical Feature of Hyperlipidemia in Patients with Central Diabetes Insipidus
- AUTOCRINE MIGRATION MECHANISM IN SMOOTH MUSCLE CELLS BY SMOOTH MUSCLE CELL : DERIVED MIGRATION FACTOR AND RELATIONSHIP TO ATHEROMA FORMATION : Arteriosclerosis : 53 Annual Scientific Meeting, Japanese Circulation Society
- -P214- STUDIES ON THE INTIMAL SMOOTH MUSCLE CELLS CULTURED FROM THE RABBIT AORTIC PLAQUE
- MACROPHAGE-DERIVED LIPID-PROTEIN PARTICLES PROMOTING LIPID ACCUMULATIONS IN SMOOTH MUSCLE CELLS : Atherosclerosis : PROCEEDINGS OF THE 50th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- Current therapeutic strategies for anal squamous cell carcinoma in Japan
- Pacemaker System Malfunction Resulting from External Electrical Cardioversion : A Case Report
- Clinical Characterization of a Case with Familial Hypobetalipoproteinemia Caused by Apo B-76, a New Truncation of Apolipoprotein B, Combined with Apo E2/E2 Phenotype
- Clinicoepidemiological manifestations of RPGN and ANCA-associated vasculitides : an 11-year retrospective hospital-based study in Japan
- Carcinoma showing thymus-like differentiation (CASTLE) with neuroendocrine differentiation
- Prediction of Severe Adverse Drug Reactions Using Pharmacogenetic Biomarkers
- Using Imaging Mass Spectrometry to Accurately Diagnose Fabry's Disease
- Genetic Polymorphisms of FCGRT Encoding FcRn in a Japanese Population and Their Functional Analysis
- Early Lower Rectal Carcinoma with Synchronous Isolated Lateral Pelvic Lymph Node Metastasis : Report of a Case
- Plasma concentrations of VCAM-1 and PAI-1 : A predictive biomarker for post-operative recurrence in colorectal cancer
- CURRENT STATUS IN THE OCCURRENCE OF POSTOPERATIVE BLEEDING, PERFORATION AND RESIDUAL/LOCAL RECURRENCE DURING COLONOSCOPIC TREATMENT IN JAPAN
- MULTICENTER QUESTIONNAIRE SURVEY ON THE CURRENT SITUATION OF COLORECTAL ENDOSCOPIC SUBMUCOSAL DISSECTION IN JAPAN
- Systemic chemotherapy for peritoneal disseminated gastric cancer with inadequate oral intake : a retrospective study
- PREVALENCE AND CLINICOPATHOLOGICAL FEATURES OF NONPOLYPOID COLORECTAL NEOPLASMS : SHOULD WE PAY MORE ATTENTION TO IDENTIFYING FLAT AND DEPRESSED LESIONS?
- Characteristics of recurrence after curative resection for T1 colorectal cancer : Japanese multicenter study
- Target biopsy or step biopsy? Optimal surveillance for ulcerative colitis : a Japanese nationwide randomized controlled trial
- MID-TERM PROGNOSIS AFTER ENDOSCOPIC RESECTION FOR SUBMUCOSAL COLORECTAL CARCINOMA : SUMMARY OF A MULTICENTER QUESTIONNAIRE SURVEY CONDUCTED BY THE COLORECTAL ENDOSCOPIC RESECTION STANDARDIZATION IMPLEMENTATION WORKING GROUP IN JAPANESE SOCIETY FOR CANCER
- Intensive Lipid-Lowering Therapy With Rosuvastatin Stabilizes Lipid-Rich Coronary Plaques : Evaluation Using Dual-Source Computed Tomography
- Aspirin Reduces Cerebrovascular Events in Type 2 Diabetic Patients With Poorly Controlled Blood Pressure : Subanalysis From the JPAD Trial
- Plaque-Stabilizing Statin Therapy Prior to Percutaneous Transluminal Angioplasty and Stenting : Reply
- Risk of lymph node metastasis in patients with pedunculated type early invasive colorectal cancer : A retrospective multicenter study